Results 121 to 130 of about 5,112,987 (375)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

ModelViz: A Model-Driven Engineering Approach for Visual Analytics System Design

IEEE Access
Visual analytics systems should be able to consolidate data from disparate sources, conduct exploratory analysis, create visualizations that suit different users, and integrate seamlessly with decision-making activities to support data-driven decision ...
Alireza Khakpour, Andrea Vazquez-Ingelmo, Ricardo Colomo-Palacios, Francisco J. Garcia-Penalvo, Antonio Martini   +4 more
doaj   +1 more source

Visual analytics of flight trajectories for uncovering decision making strategies [PDF]

, 2018
In air traffic management and control, movement data describing actual and planned flights are used for planning, monitoring and post-operation analysis purposes with the goal of increased efficient utilization of air space capacities (in terms of delay ...
Andrienko, G., Andrienko, N., Cordero Garcia, J. M., Fuchs, G., Herranz, R., Marcos, R., Scarlatti, D., Vouros, G. A.   +7 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Information Characteristics and Social Media Information Sharing: Insights From Elaboration Likelihood Model (ELM) for Misinformation Mitigation

IEEE Access
The rapid dissemination of information on social media has many positives but has also raised significant concerns regarding misinformation, making it crucial to understand the factors driving information-sharing behavior.
Juanita Zainudin, Nazlena Mohamad Ali, Alan F. Smeaton, Mohamad Taha Ijab   +3 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Intervention Strategies for Misinformation Sharing on Social Media: A Bibliometric Analysis

IEEE Access
Widely distributed misinformation shared across social media channels is a pressing issue that poses a significant threat to many aspects of society’s well-being.
Juanita Zainudin, Nazlena Mohamad Ali, Alan F. Smeaton, Mohamad Taha Ijab   +3 more
doaj   +1 more source

Fostering Decision-Making Processes in Health Ecosystems Through Visual Analytics and Machine Learning

, 2022
Francisco José García‐Peñalvo, Andrea Vázquez‐Ingelmo, Alicia García‐Holgado   +2 more
openalex   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Using Eye Tracking to Explore Differences in Map-Based Spatial Ability between Geographers and Non-Geographers

ISPRS International Journal of Geo-Information, 2018
In this article, we use eye-tracking methods to analyze the differences in spatial ability between geographers and non-geographers regarding topographic maps, as reflected in the following three aspects: map-based spatial localization, map-based spatial ...
Weihua Dong, Liangyu Zheng, Bing Liu, Liqiu Meng   +3 more
doaj   +1 more source