Results 151 to 160 of about 5,112,987 (375)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Review of visual analytics methods for food safety risks. [PDF]

open access: yesNPJ Sci Food, 2023
Chen Y, Wu C, Zhang Q, Wu D.
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

A Visual Analytics Approach to Debugging Cooperative, Autonomous Multi-Robot Systems' Worldviews [PDF]

open access: green, 2020
Suyun lSandrar Bae   +4 more
openalex   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Integrating 3D city data through knowledge graphs

open access: yesGeo-spatial Information Science
CityGML is a widely adopted standard for representing and exchanging 3D city models. The representation of semantic and topological properties in CityGML makes it possible to query such 3D city data for analysis in various applications. Nevertheless, the
Linfang Ding   +8 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

BioMOBS: A multi-omics visual analytics workflow for biomolecular insight generation. [PDF]

open access: yesPLoS One, 2023
Heylen D   +4 more
europepmc   +1 more source

Semantic Analytics Visualization

open access: yes, 2006
In this paper we present a new tool for semantic analytics through 3D visualization called “Semantic Analytics Visualization” (SAV). It has the capability for visualizing ontologies and meta-data including annotated web-documents, images, and digital media such as audio and video clips in a synthetic three-dimensional semi-immersive environment.
Deligiannidis, Leonidas   +2 more
openaire   +4 more sources

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