Results 201 to 210 of about 2,285,675 (298)

OmicsView: Omics data analysis through interactive visual analytics. [PDF]

Comput Struct Biotechnol J, 2022
Casey F, Negi S, Zhu J, Sun YH, Zavodszky M, Cheng D, Lin D, John S, Penny MA, Sexton D, Zhang B.   +10 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Advancing open-source visual analytics in digital pathology: A systematic review of tools, trends, and clinical applications. [PDF]

J Pathol Inform
Ahmad Z, Alzubaidi M, Al-Thelaya K, Calí C, Boughorbel S, Schneider J, Agus M.   +6 more
europepmc   +1 more source

OmicsNet 2.0: a web-based platform for multi-omics integration and network visual analytics. [PDF]

Nucleic Acids Res, 2022
Zhou G, Pang Z, Lu Y, Ewald J, Xia J.
europepmc   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

A Visual Analytics Framework for Assessing Interactive AI for Clinical Decision Support. [PDF]

Pac Symp Biocomput
Prince EW, Hankinson TC, Görg C.
europepmc   +1 more source

Visual Analytics Dashboard Promises to Improve Hypertension Guideline Implementation. [PDF]

Am J Hypertens, 2021
Fadel RA, Ross J, Asmar T, Sridasyam K, Demertzis Z, Ahluwalia G, Roumayah T, Scott M, Ibrahim H, Hammoudeh R, Gandhi N, Flynn M, Haftka-George A, Heidemann D, Sims S, Levy P, Miller J.   +16 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Complementary, alternative, and integrative medicine therapies for knee osteoarthritis: a visual analytics analysis of the research domain. [PDF]

Front Med (Lausanne)
Luo C, Wang J, Guo J.
europepmc   +1 more source

Novel visual analytics approach for chromosome territory analysis. [PDF]

PeerJ, 2021
Tkacz MA, Chromiński K, Idziak-Helmcke D, Robaszkiewicz E.   +3 more
europepmc   +1 more source