Results 51 to 60 of about 6,103 (181)

Nanogel-Facilitated In-Situ Delivery of a Cataract Inhibitor

Biomolecules, 2021
Cataracts are a leading cause of blindness worldwide. Surgical removal of cataracts is a safe and effective procedure to restore vision. However, a large number of patients later develop vision loss due to regrowth of lens cells and subsequent ...
Dixa Gautam, Michelle G. Pedler, Devatha P. Nair, Jonathan Mark Petrash   +3 more
doaj   +1 more source

Epithelial-mesenchymal transdifferentiation in pediatric lens epithelial cells [PDF]

, 2018
PURPOSE. Posterior capsule opacification (PCO) is a complication after cataract surgery, particularly in children. Epithelial-mesenchymal transition (EMT) of lens epithelial cells, mediated by transforming growth factor beta (TGF beta), contributes to ...
Keckeis, Susanne, Reichhart, Nadine, Salchow, Daniel J., Strauß, Olaf, Wernecke, Laura   +4 more
core   +1 more source

Three-Dimensional Myocardial Perfusion Maps by Contrast Echocardiography [PDF]

, 1997
We evaluated the clinical applicability of a system for three-dimensional (3-D) display of a perfusion map following myocardial contrast echocardiography (MCE). The system was used in 12 patients (9 males and 3 females, mean age 52 ± 10 years) undergoing
Bourdillon PDV, Cate FJ, Cate FJ, Cate FJ, Garvin AA, Kasprzak JD, Kondo S, Lang R, Miller DD, Ragosta M, Reisner S, Sinha S, Vandenberg BF, Zwehl W   +13 more
core   +3 more sources

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months

Indian Journal of Ophthalmology, 2018
Purpose: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants
Mithila Negalur, Virender Sachdeva, Srividya Neriyanuri, Mohammed Hasnat Ali, Ramesh Kekunnaya   +4 more
doaj   +1 more source

Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho, Alexis E. McFeely, Daniel Skinner, Shaoyan Zhang, Justin Hedvat, Weslee Ping‐ay, Daniel M. Beswick, Justin H. Turner, Bradford A. Woodworth, Jie Xu   +9 more
wiley   +1 more source

Assessing Surgical Extent in Endoscopic Sinus Surgery: A Scoping Review of Scoring Systems

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Endoscopic sinus surgery (ESS) varies substantially in the extent of surgical dissection performed, even when described under the same procedural label. In chronic rhinosinusitis, this heterogeneity may influence postoperative outcomes, revision rates, and response to biologic therapies.
Alexander Lein, Marie T. Ehrgott, Linda Liu, Archana Jaiswal, Rajiv K. Bhalla, Noel Ayoub, Faris F. Brkic, David T. Liu   +7 more
wiley   +1 more source

Innovations in pediatric cataract surgery

Indian Journal of Ophthalmology, 2017
Advances in technology have made surgery in children safer and faster. The management of pediatric cataract has made rapid progress in the past decade with the availability of safer anesthesia, newer technique's, more predictable intraocular lens (IOL ...
Sudarshan Kumar Khokhar, Ganesh Pillay, Esha Agarwal, Manish Mahabir   +3 more
doaj   +1 more source

Effect of corneal light scatter on vision: a review of the literature [PDF]

, 2016
The cornea is the transparent connective tissue window at the front of the eye. The physiological role of the cornea is to conduct external light into the eye, focus it, together with the lens, onto the retina, and to provide rigidity to the entire ...
MARAONE, GIORGIA, SPADEA, LEOPOLDO, Tognetto, Daniele, VERBOSCHI, FRANCESCA, VINGOLO, Enzo Maria   +4 more
core   +3 more sources

Automatic segmentation of multiple cardiovascular structures from cardiac computed tomography angiography images using deep learning. [PDF]

, 2020
OBJECTIVES:To develop, demonstrate and evaluate an automated deep learning method for multiple cardiovascular structure segmentation. BACKGROUND:Segmentation of cardiovascular images is resource-intensive.
Al'Aref, Subhi J, Andreini, Daniele, Baskaran, Lohendran, Bax, Jeroen J, Berman, Daniel S, Budoff, Matthew J, Cademartiri, Filippo, Chang, Hyuk-Jae, Chinnaiyan, Kavitha, Choi, Jeong W, Choi, Jung Hyun, Chun, Eun Ju, Conte, Edoardo, Dunham, Simon, Gottlieb, Ilan, Hadamitzky, Martin, Kim, Yong-Jin, Lee, Benjamin C, Lee, Byoung Kwon, Lee, Sang-Eun, Leipsic, Jonathon A, Lin, Fay Y, Maffei, Erica, Maliakal, Gabriel, Marques, Hugo, Min, James K, Mosadegh, Bobak, Narula, Jagat, Pontone, Gianluca, Raff, Gilbert L, Samady, Habib, Shaw, Leslee J, Shin, Sanghoon, Stone, Peter H, Sung, Ji Min, Virmani, Renu, Xu, Zhuoran   +36 more
core   +3 more sources