Results 41 to 50 of about 665,005 (335)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

First visual orbit for the prototypical colliding-wind binary WR 140 [PDF]

, 2011
Wolf-Rayet stars represent one of the final stages of massive stellar evolution. Relatively little is known about this short-lived phase and we currently lack reliable mass, distance, and binarity determinations for a representative sample.
Baron, F., Berger, J. P., Brummelaar, T. ten, Kraus, S., McAlister, H., Millan-Gabet, R., Monnier, J. D., Pedretti, E., Ridgway, S., Schloerb, F. P., Sturmann, J., Sturmann, L., Tannirkulam, A., Traub, W., Turner, N., Williams, P. M., Zhao, Ming   +16 more
core   +5 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Performance of the SOAR Speckle Instrument

The Astronomical Journal
The High Resolution Camera (HRCam) speckle imager at the 4.1 m Southern Astrophysical Research telescope is a highly productive instrument that has accumulated about 40K observations to date.
Andrei Tokovinin
doaj   +1 more source

Data driven visual tracking via representation learning and online multi‐class LPBoost learning

IET Computer Vision, 2016
Visual object tracking is a challenging task due to two intractable problems: visual appearance representation and online update model. Existing approaches often operate appearance model based on hand‐crafted features with discriminative feature ...
Xian Yang, Shoujue Wang
doaj   +1 more source

Interferometric Evidence for Resolved Warm Dust in the DQ Tau System [PDF]

, 2009
We report on near-infrared (IR) interferometric observations of the double-lined pre-main sequence (PMS) binary system DQ Tau. We model these data with a visual orbit for DQ Tau supported by the spectroscopic orbit & analysis of \citet{Mathieu1997 ...
Akeson, R., Bary, J., Boden, A., Carpenter, J., Ciardi, D., Sargent, A., Skrutskie, M.   +6 more
core   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Detecting New Visual Binaries in Gaia DR3 with Gaia and Two Micron All Sky Survey (2MASS) Photometry. II. Speckle Observations of 16 Low-separation Systems

The Astronomical Journal
Here we present speckle observations of 16 low-separation ( s < 30 au) high-probability candidate binaries from the catalog by Medan et al., where secondaries typically lack astrometric solutions in Gaia. From these speckle observations, we find a second
Ilija Medan, Sébastien Lépine, Zachary Hartman, Keivan G. Stassun   +3 more
doaj   +1 more source

Color Visual Secret Sharing for QR Code with Perfect Module Reconstruction

Applied Sciences, 2019
Visual secret sharing is a secret sharing scheme where the decryption requires no computation. It has found many applications in online transaction security, privacy protection, and bar code security, etc.
Tao Liu, Bin Yan, Jeng-Shyang Pan
doaj   +1 more source

Minimalist AdaBoost for blemish identification in potatoes [PDF]

, 2010
We present a multi-class solution based on minimalist Ad- aBoost for identifying blemishes present in visual images of potatoes. Using training examples we use Real AdaBoost to rst reduce the fea- ture set by selecting ve features for each class, then
D. Unay, E.G. De Haan, L. Zhou, M. Barnes, P.H. Heinemann, R. Bolle, Y. Freund, Y. Tao, Y. Tao, Z. Guannan   +9 more
core   +1 more source