Results 111 to 120 of about 597,872 (309)

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Classification of Real and Imagined Sounds in Early Visual Cortex

i-Perception, 2011
Early visual cortex has been thought to be mainly involved in the detection of low-level visual features. Here we show that complex natural sounds can be decoded from early visual cortex activity, in the absence of visual stimulation and both when sounds
Petra Vetter
doaj   +1 more source

Design principles of columnar organization in visual cortex [PDF]

, 1994
Visual space is represented by cortical cells in an orderly manner. Only little variation in the cell behavior is found with changing depth below the cortical surface, that is, all cells in a column with axis perpendicular to the cortical plane have ...
Niebur, Ernst, Wörgötter, Florentin
core  

Adaptive Filtering Enhances Information Transmission in Visual Cortex

, 2006
Sensory neuroscience seeks to understand how the brain encodes natural environments. However, neural coding has largely been studied using simplified stimuli.
A Kohn, AA Emondi, AB Saul, AL Fairhall, Andrei V. Kurgansky, BC Skottun, C Blakemore, D Chander, D Smyth, DG Albrecht, DJ Field, DJ Field, DL Ringach, DL Ruderman, DW Dong, EP Simoncelli, F Rieke, FE Theunissen, FE Theunissen, G Felsen, Hiroki Sugihara, I Ohzawa, JA Movshon, JD Victor, JJ Atick, Kenneth D. Miller, L Maffei, Michael P. Stryker, MJ Nolt, MJ Wainwright, MN Kvale, MP Sceniak, N Brenner, N Brenner, NC Rust, R Baddeley, R de Boer, R Shapley, RM Shapley, SA Baccus, Sergei P. Rebrik, SG Solomon, SM Smirnakis, SP Brown, SV David, T Hosoya, T Sharpee, Tatyana O. Sharpee, V Dragoi, Y Dan   +49 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Visual Brain and Visual Perception: How Does the Cortex Do Perceptual Grouping? [PDF]

, 1996
How the brain generates visual percepts is a central problem in neuroscience. We propose a detailed neural model of how LGN and the interblob cortical stream through V1 and V2 generate context-sensitive perceptual groupings from visual inputs.
Grossberg, Stephen, Mingolla, Ennio, Ross, William   +2 more
core   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Surface-Based Analyses of Anatomical Properties of the Visual Cortex in Macular Degeneration.

PLoS ONE, 2016
IntroductionMacular degeneration (MD) can cause a central visual field defect. In a previous study, we found volumetric reductions along the entire visual pathways of MD patients, possibly indicating degeneration of inactive neuronal tissue.
Doety Prins, Tina Plank, Heidi A Baseler, André D Gouws, Anton Beer, Antony B Morland, Mark W Greenlee, Frans W Cornelissen   +7 more
doaj   +1 more source

Attentional load and sensory competition in human vision: Modulation of fMRI responses by load fixation during task-irrelevant stimulation in the peripheral visual field. [PDF]

, 2005
Perceptual suppression of distractors may depend on both endogenous and exogenous factors, such as attentional load of the current task and sensory competition among simultaneous stimuli, respectively. We used functional magnetic resonance imaging (fMRI)
Dolan, R.J., Driver, J., Hutton, C., Maravita, A., Schwartz, S., Veilleumier, P.   +5 more
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