Results 151 to 160 of about 294,373 (174)

Cortical direction selectivity increases from the input to the output layers of visual cortex. [PDF]

PLoS Biol
Dai W, Wang T, Li Y, Yang Y, Zhang Y, Wu Y, Zhou T, Yu H, Li L, Wang Y, Wang G, Xing D.   +11 more
europepmc   +1 more source

NIR‐II Fluorescent Protein Created by In Situ Albumin‐Tagging for Sensitive and Specific Imaging of Blood‐Brain Barrier Disruption

Advanced Science, EarlyView.
The breakdown of the blood‐brain barrier (BBB) after cerebral ischemia can cause brain injury and induce potentially fatal consequences. Currently, there exist few dependable and low‐cost imaging techniques for visualizing the BBB. This investigation effectively engineered an albumin‐specific covalently tagged near‐infrared‐II (NIR‐II) dye, serving as ...
Jiajun Xu, Yijing Du, Ningning Zhu, Jia Li, Yuewei Zhang, Ding Zhou, Shoujun Zhu   +6 more
wiley   +1 more source

Anatomical and molecular development of the human primary visual cortex. [PDF]

Front Cell Neurosci
Murphy KM, Monteiro L.
europepmc   +1 more source

Neuromorphic Computing Using Synaptic Plasticity of Supercapacitors

Advanced Science, EarlyView.
A neuromorphic computing pathway based on supercapacitors is presented. MXene Ti₃C₂Tx supercapacitors demonstrate voltage responses under current stimuli, thus exhibiting synaptic plasticity. Energy is stored during response enhancement and released once the response declines.
Ling Wang, Xing Liu, Guangcai Zhang, Fuxun Qi, Xi Chen   +4 more
wiley   +1 more source

APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice. [PDF]

Commun Biol
Anderle S, Bonnar O, Henderson J, Shaw K, Chagas AM, McMullan L, Webber A, McGowan K, King SL, Hall CN.   +9 more
europepmc   +1 more source

Elasticity‐Driven Nanomechanical Interaction to Improve the Targeting Ability of Lipid Nanoparticles in the Malignant Tumor Microenvironment

Advanced Science, EarlyView.
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee, Loi Nguyen Dang, Jinsol Choi, Haesoo Kim, Lyndon Bastatas, Soyeun Park   +5 more
wiley   +1 more source

Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex. [PDF]

Proc Natl Acad Sci U S A
Xie F, Jain S, Xu R, Butrus S, Tan Z, Xu X, Shekhar K, Zipursky SL.   +7 more
europepmc   +1 more source

The Dynamic Landscape of 3′‐UTR Alternative Polyadenylation Across Mouse Fetal Development and Anatomy

Advanced Science, EarlyView.
This work maps 3′‐UTR APA across mouse fetal development and tissues, identifying conserved sequence determinants that influence pAS choice. In fetal brain tissues, complex APA dynamics during development are potentially regulated by RBPs like Rbm38, which restrict distal pAS usage.
Qin Wang, Xin Chen, Xiao‐Ou Zhang
wiley   +1 more source

Sensory experience steers representational drift in mouse visual cortex. [PDF]

Nat Commun
Bauer J, Lewin U, Herbert E, Gjorgjieva J, Schoonover CE, Fink AJP, Rose T, Bonhoeffer T, Hübener M.   +8 more
europepmc   +1 more source

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

Advanced Science, EarlyView.
This study presents a novel approach for intraoperative identification of the IDH1 genotype in glioma patients using a surface‐enhanced Raman scattering (SERS) probe to measure glutathione and hydrogen peroxide. By integrating AI‐driven deep learning algorithms, the method achieves rapid and accurate genotype differentiation, offering the potential to ...
Hang Yin, Xin Zhang, Zheng Zhao, Chong Cao, Minhua Xu, Suhongrui Zhou, Tian Xuan, Ziyi Jin, Limei Han, Yang Fan, Cong Wang, Xiao Zhu, Ying Mao, Jinhua Yu, Cong Li   +14 more
wiley   +1 more source