Results 151 to 160 of about 526,629 (263)

3D‐Printed Titanium Trabecular Scaffolds with Sustained Release of Hypoxia‐Induced Exosomes for Dual‐Mimetic Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This study presents 3D‐printed Ti‐6Al‐4V trabecular scaffolds combined with hypoxia‐induced exosomes encapsulated in PEGDA/GelMA microspheres for sustained release. The scaffolds mimic the structure of natural bone, while the exosome delivery system enhances osteogenesis and angiogenesis, significantly promoting bone regeneration and offering a ...
Lincong Luo   +14 more
wiley   +1 more source

Locus Coeruleus Noradrenergic‐Spinal Projections Contribute to Electroacupuncture‐Mediated Antinociception in Postoperative Pain in Mice

open access: yesAdvanced Science, EarlyView.
How locus coeruleus noradrenergic‐spinal projections and subsequent α2A adrenoceptors‐CaMKII signaling cascades contribute to electroacupuncture‐induced antinociception in postoperative pain in mice is described. Abstract Postoperative pain remains a significant challenge in healthcare.
Wen‐Guang Chu   +13 more
wiley   +1 more source

A column-like organization for ocular dominance in mouse visual cortex. [PDF]

open access: yesNat Commun
Goltstein PM   +3 more
europepmc   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Cerebral perfusion differences in the visual cortex and fusiform subregions across the psychosis spectrum. [PDF]

open access: yesFront Psychiatry
Sritharan J   +17 more
europepmc   +1 more source

The SlDOF9‐SlSWEET17 Module: a Switch for Controlling Sugar Distribution Between Nematode Induced Galls and Roots in Tomato

open access: yesAdvanced Science, EarlyView.
Root‐knot nematode (RKN) disease seriously affects the yield and quality of vegetable crops. SlDOF9‐SlSWEET17 model helps plants resist RKN infection during early stage by switching off the sugar transport capacity of other SlSWEET proteins that are hijacked by RKNs.
Xiaoyun Wang   +14 more
wiley   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy