Results 151 to 160 of about 280,553 (265)

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Continuous cell-type diversification in mouse visual cortex development. [PDF]

Nature
Gao Y, van Velthoven CTJ, Lee C, Thomas ED, Mathieu R, Ayala AP, Barta S, Bertagnolli D, Campos J, Cardenas T, Carey D, Casper T, Chakka AB, Chakrabarty R, Chiang M, Ching L, Clark M, Desierto MJ, Ferrer R, Gloe J, Goldy J, Guilford N, Guzman J, Halterman CR, Hastings SD, Hirschstein D, Ho W, James K, Juneau Z, Martin N, McCue R, Meyerdierks E, Mitchell AC, Nagra JS, Nguy B, Nguyen TN, Olsen P, Oyama AA, Pena N, Quon J, Ren Q, Ruiz A, Shapovalova NV, Sulc J, Torkelson A, Tran A, Tung H, Valera Cuevas N, Wang J, Ariza J, McMillen DAM, Waters J, Kunst M, Ronellenfitch K, Levi B, Hawrylycz MJ, Pagan C, Dee N, Smith KA, Tasic B, Yao Z, Zeng H.   +61 more
europepmc   +1 more source

Visual Cortex Disorder [PDF]

, 2020
openaire   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Single-cell sequencing reveals reversible glial remodeling in the visual cortex during visual deprivation and recovery. [PDF]

Front Immunol
Gong X, Feng J, Xu Z, Xie Y, Han Y, Li J, Tang G, Liu Y, Dong X, Li S, Zhang J, Wang J, Liu R, Song J, Bi H.   +14 more
europepmc   +1 more source

Injectable Chondroitin Sulfate Methacrylate Hydrogel Microspheres Co‐Loaded with GLPM Nanozyme, Dexamethasone, and Stem Cells for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng, Ying Fang, Hongwei Yu, Yicheng Wang, Yunze Xu, Chunxiao Shi, Haike Xia, Ranjith Kumar Kankala, Aizheng Chen, Shibin Wang, Chaoping Fu   +10 more
wiley   +1 more source

Rethinking category-selectivity in human visual cortex. [PDF]

Cogn Neurosci
Ritchie JB, Wardle SG, Vaziri-Pashkam M, Kravitz DJ, Baker CI.   +4 more
europepmc   +1 more source

Primary visual cortex

, 2015
Daniel Loh, Craig Hacking, Yuranga Weerakkody   +2 more
openaire   +1 more source

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

Advanced Science, EarlyView.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi, Xiaoyi Wang, Huichun Luo, Ziteng Yue, Tianjiao Deng, Yuhang Liu, Xinxin Chen, Jianxu Zhao, Luo Shi, Ning Ma, Lingyan Mao, Jing Ding, Jiwen Xu, Ti‐Fei Yuan, Sheng Wang, Fang Yuan   +15 more
wiley   +1 more source

Emergence of a contrast-invariant representation of naturalistic texture in macaque visual cortex. [PDF]

Proc Natl Acad Sci U S A
Lee GM, Majaj NJ, Deliz CLR, Kiorpes L, Movshon JA.   +4 more
europepmc   +1 more source