Results 31 to 40 of about 288,865 (267)

Visual perception: Spotlight on the primary visual cortex [PDF]

open access: yesCurrent Biology, 1999
Visual search tasks appear to involve spatially selective attention to the target, but evidence for attentional modulation in the visual area with the most precise retinotopic organization V1 has been elusive. Recent imaging studies show that spatial attention can indeed enhance visual responses in human V1.
Sengpiel, F., Hubener, M.
openaire   +3 more sources

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte   +5 more
wiley   +1 more source

High-level visual prediction errors in early visual cortex.

open access: yesPLoS Biology
Perception is shaped by both incoming sensory input and expectations derived from our prior knowledge. Numerous studies have shown stronger neural activity for surprising inputs, suggestive of predictive processing.
David Richter   +2 more
doaj   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Metabolic changes in the visual cortex of binocular blindness macaque monkeys: a proton magnetic resonance spectroscopy study. [PDF]

open access: yesPLoS ONE, 2013
PURPOSE: To evaluate proton magnetic resonance spectroscopy ((1)H-MRS) in a study of cross-modal plasticity in the visual cortex of binocular blindness macaque monkeys.
Lingjie Wu   +6 more
doaj   +1 more source

The human visual system differentially represents subjectively and objectively invisible stimuli.

open access: yesPLoS Biology, 2021
The study of unconscious processing requires a measure of conscious awareness. Awareness measures can be either subjective (based on participant's report) or objective (based on perceptual performance).
Timo Stein   +3 more
doaj   +1 more source

Hebbian synapses in visual cortex [PDF]

open access: yesThe Journal of Neuroscience, 1994
We discovered in slices of rat visual cortex that reliable long-term potentiation (LTP) of synaptic responses in layer III could be elicited by theta burst stimulation delivered to a site in the middle of the cortical thickness, corresponding mainly to layer IV.
A, Kirkwood, M F, Bear
openaire   +2 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The development of visual areas depends differently on visual experience. [PDF]

open access: yesPLoS ONE, 2013
Visual experience plays an important role in the development of the visual cortex; however, recent functional imaging studies have shown that the functional organization is preserved in several higher-tier visual areas in congenitally blind subjects ...
Wen Qin   +3 more
doaj   +1 more source

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