Results 41 to 50 of about 1,748,226 (269)
Social Sciences, 2019 Since the turn of the millennium researchers have access to an ever-increasing pool of novel types of video recordings. People use camcorders, mobile phone cameras, and even drones to film and photograph social life, and many public spaces are under ...
Anne Nassauer, Nicolas M. Legewie
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The Image of City as Seen through Social Media Photographs: A Case Study of the Historical Context of Tabriz [PDF]
توسعه پایدار شهریThe image of a city comprises the beliefs, perceptions, and imaginations that citizens hold about their city. These mental images provide a framework for urban planners to propose better futures for the city.
Mahsa Chizfahm Daneshmandian +3 more
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Machine Learning and Knowledge Extraction, 2023 Implantable Cardiac Monitor (ICM) devices are demonstrating, as of today, the fastest-growing market for implantable cardiac devices. As such, they are becoming increasingly common in patients for measuring heart electrical activity.
Amnon Bleich +4 more
doaj +1 more source
IEEE Computer Graphics and Applications, 2013 Almost all fields of study and practice sooner or later will confront the big-data problem. Visualization has proven effective for not only presenting essential information in vast amounts of data but also driving complex analyses. Big-data analytics and discovery present new research opportunities to the computer graphics and visualization community ...
Daniel A. Keim, Huamin Qu, Kwan-Liu Ma
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Social SciencesHidradenitis suppurativa (HS) is a chronic, inflammatory, and often debilitating skin condition that includes painful “flares” in the groin, genital, and underarms.
Natalie Ingraham +2 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source