Results 191 to 200 of about 2,196,079 (289)

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Syncope and Scar in a Former Elite Basketball Player. [PDF]

JACC Case Rep
Garba DL, Aronis KN, Barouch LA, Sahbaz J.   +3 more
europepmc   +1 more source

Heart‐Rate Variability and Its Role in Non‐Cardiac Surgery Perioperative Care: Scoping Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Heart rate variability (HRV) is a non‐invasive method of assessing autonomic function. Those with autonomic dysfunction may be at heightened risk of peri‐operative complications due to sympatho‐parasympathetic imbalance. This review summarises the clinical applications of HRV, approaches to how it is measured, and its role in ...
Reuben Veysey‐Smith, Ashmit Bhardwaj, David G. Jayne, Stephen J. Chapman   +3 more
wiley   +1 more source

Sex-independent visual evoked potential complexity. [PDF]

Clin Neurophysiol Pract
Lisowski Ł, Łabieniec Ł, Lisowska J, Andrejczuk A, Zalewski D, Konopińska J.   +5 more
europepmc   +1 more source

Clinical and molecular features of PRCD‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin, Karolina Kaminska, Marco Cattaneo, Enrico Ambrosini, Carmen Ayuso, Almudena Ávila‐Fernández, Béatrice Bocquet, Luisa Coutinho‐Santos, Benedetto Falsini, Lidia Fernandez‐Caballero Palomeque, Bohdan Kousal, Petra Liskova, Inmaculada Martín‐Mérida, María Juliana Ballesta‐Martínez, Daan Panneman, Susanne Roosing, Isabelle Meunier, José M. Millán, Monika Pankievič, Irene Perea‐Romero, Virginie Peter, Giorgio Placidi, Cristina Santos, Francesca Simonelli, Ana Berta Sousa, Francesco Testa, Marie Vajter, Marianna Weener, Mathieu Quinodoz, Carlo Rivolta, Giacomo Calzetti   +30 more
wiley   +1 more source

Cholinergic-dependent dopamine signals in mouse dorsomedial striatum are regulated by frontal but not sensory cortices. [PDF]

Nat Commun
Goldbach HC, Rimondini R, Swanson ES, Shin JH, Authement ME, Anderson LG, Kwon HB, Paletzki R, Gerfen CR, Amarante LM, Krauzlis RJ, Alvarez VA.   +11 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Incidental Diagnosis of TTR Amyloidosis During Left Bundle Branch Pacing Implantation: When Electrophysiology Meets Cardiomyopathy. [PDF]

JACC Case Rep
Costantino J, Proietti P, Ballatore F, Marchionni G, Zuccaro LM, Campoli M, Porcelli D, Romani B, Giordano C, Chimenti C.   +9 more
europepmc   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Bilateral Multifocal Serous Retinal Pigment Epithelial Detachments Coexisting With Generalized Rod-Cone Dysfunction Resembling Retinitis Pigmentosa. [PDF]

Cureus
Fukagai H, Nariya Y, Sugimoto K, Aoki S.
europepmc   +1 more source