Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Age-Related Discrimination of Visual-Evoked Potentials Using Cross-Coherence Analysis. [PDF]
Almurshedi AF.
europepmc +1 more source
Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr +6 more
wiley +1 more source
Diagnostic accuracy of isolated-check visual evoked potentials for glaucoma: a systematic review and meta-analysis. [PDF]
Li Y, Lu Y, Lin T.
europepmc +1 more source
Synchronized Imaging of Hydrogen Peroxide and Hydroxyl Radical in Pyroptosis and Epilepsy
A dual‐responsive fluorescent probe, HH, enables synchronized visualization of H2O2 and •OH through spectrally resolved green and red channels. By tracking redox dynamics in pyroptosis and epilepsy models, HH reveals ROS elevation during seizure‐like pathology and supports evaluation of antioxidant and antiepileptic therapeutic interventions.
Yabing Gan +9 more
wiley +1 more source
Frequency domain analysis of steady-state visual evoked potentials in dogs with optic neuritis: a pilot study. [PDF]
Lee TG, Kim JY.
europepmc +1 more source
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun +13 more
wiley +1 more source
Predicting visual acuity of treated ocular trauma based on pattern visual evoked potentials by machine learning models. [PDF]
Hao H +5 more
europepmc +1 more source
Bioinspired Ionochromic Neuromorphic Transistors for Robotic Intelligent Perception
A bioinspired ionochromic neuromorphic transistor couples synaptic conductance modulation with reversible color change through voltage‐controlled ion doping in P3HT/ion gel, mimicking biological synaptic plasticity, and chameleon‐like color regulation.
Quanxing Yao +10 more
wiley +1 more source
Analysis of Intraoperative Visual Evoked Potentials for Inclusion of Unstable Electroretinograms. [PDF]
Cochard E +3 more
europepmc +1 more source

