Results 101 to 110 of about 6,775,324 (288)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Pain Memory “Trace”: Cumulative Pain Perception and Damping During Fight-or-Flight Response Modeled with a Lotka-Volterra-Style Coupled Feedback Control Loop System

Journal of Pain Research
Wolfgang Fink,1 Robert B Raffa2,3 1Visual and Autonomous Exploration Systems Research Laboratory, University of Arizona, Tucson, AZ, USA; 2Temple University (Emeritus), Philadelphia, PA, USA; 3University of Arizona (Adjunct), Tucson, AZ ...
Fink W, Raffa RB
doaj  

A novel perceptual trait: gaze predilection for faces during visual exploration

Scientific Reports, 2019
Humans are social animals and typically tend to seek social interactions. In our daily life we constantly move our gaze to collect visual information which often includes social information, such as others’ emotions and intentions.
Nitzan Guy, Hagar Azulay, Rasha Kardosh, Yarden Weiss, Ran R. Hassin, S. Israel, Y. Pertzov   +6 more
semanticscholar   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Challenges and strategies for the visual exploration of complex environmental data

International Journal of Digital Earth, 2017
In this opinion paper, we, a group of scientists from environmental-, geo-, ocean- and information science, argue visual data exploration should become a common analytics approach in Earth system science due to its potential for analysis and ...
Carolin Helbig, Doris Dransch, Michael Böttinger, Colin Devey, Antonie Haas, Mario Hlawitschka, Claudia Kuenzer, Karsten Rink, Christian Schäfer-Neth, Gerik Scheuermann, Tom Kwasnitschka, Andrea Unger   +11 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Fast training of self organizing maps for the visual exploration of molecular compounds [PDF]

, 2007
Visual exploration of scientific data in life science area is a growing research field due to the large amount of available data. The Kohonen’s Self Organizing Map (SOM) is a widely used tool for visualization of multidimensional data.
Rizzo, Riccardo, Urso, Alfonso, GIUSEPPE DI FATTA, RICCARDO RIZZO, URSO, Alberto, Gaglio, Salvatore, Fiannaca, Antonino, Alfonso Urso, Antonino Fiannaca, Salvatore Gaglio, Di Fatta, Giuseppe   +10 more
core   +1 more source

Post-clustering Prioritization Framework for Autonomous Decision Making in the Absence of Ground Truth via Hypothetical Probing

International Journal of Prognostics and Health Management
A generic prioritization framework is introduced for addressing the problem of automated prioritization of region of interest or target selection. The framework is based on the assumption that clustering of preliminary data for preidentified regions or ...
Wolfgang Fink, Karm Al Hajhog
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

OrthoInspector: comprehensive orthology analysis and visual exploration

BMC Bioinformatics, 2011
Background The accurate determination of orthology and inparalogy relationships is essential for comparative sequence analysis, functional gene annotation and evolutionary studies.
Lecompte Odile, Poch Olivier, Thompson Julie D, Linard Benjamin   +3 more
doaj   +1 more source