Results 31 to 40 of about 722,173 (312)
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
An algorithm for visual fields
Survey of Ophthalmology, 1980 The authors present an algorithm, or sequential strategy, for the performance and interpretation of visual fields. Based on the principle that particular areas of the visual field are relatively vulnerable and that particular defect configurations are relatively more diagnostic, the strategy proposes certain "core maneuvers" for all initial ...
Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida USA ( host institution ) +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
DiagnosticsThe aim of this study was to compare the effectiveness of trabeculectomy (TE) and deep sclerectomy (DS) in lowering intraocular pressure (IOP) and thereby preserving visual field and peripapillary retinal nerve fiber layer (RNFL) tissue in primary open ...
Valentin Pfeiffer +6 more
doaj +1 more source
Biomedical Papers, 2021 Background. Hypertensive glaucoma (HTG) causes damage to the retinal ganglion cells and eventually to the entire visual pathway due to high intraocular pressure (IOP).
Marketa Zakova +3 more
doaj
Susac′s syndrome: First from India and youngest in the world
Indian Journal of Ophthalmology, 2013 A two and half year old female was admitted at the emergency room suffering from gradually worsening headache followed by nausea. The child presented with reduced level of consciousness and bilateral hypoacusis. The patient was lethargic.
Gunjan Prakash +3 more
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Evaluation of refractive correction for standard automated perimetry in eyes wearing multifocal contact lenses [PDF]
International Journal of Ophthalmology, 2017 AIM: To evaluate the refractive correction for standard automated perimetry (SAP) in eyes with refractive multifocal contact lenses (CL) in healthy young participants. METHODS: Twenty-nine eyes of 29 participants were included.
Kazunori Hirasawa +4 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Delta Journal of Ophthalmology, 2019 Background Glaucoma is a multifactorial chronic optic neuropathy characterized by typical optic nerve morphological changes and alterations of the visual field (VF).
Madeha A Kamel +2 more
doaj +1 more source