Results 31 to 40 of about 786,215 (266)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Visual Field

Collegium antropologicum, 2013
This article is dedicated to main information about visual field, monocular and binocular ranges of visual field including their defects. Visual field loss may occur to disease of the eye, optic nerve or brain. Typical changes are present at glaucoma and macular degeneration. Visual pathway is also mentioned.
Sokolová Šidlová, Jana, Beneš, Pavel, Holoubková, Zuzana   +2 more
openaire   +3 more sources

Visual Acoustic Fields

CoRR
Objects produce different sounds when hit, and humans can intuitively infer how an object might sound based on its appearance and material properties. Inspired by this intuition, we propose Visual Acoustic Fields, a framework that bridges hitting sounds and visual signals within a 3D space using 3D Gaussian Splatting (3DGS).
Yuelei Li, Hyunjin Kim 0004, Fangneng Zhan, Ri-Zhao Qiu, Mazeyu Ji, Xiaojun Shan, Xueyan Zou, Paul Liang, Hanspeter Pfister, Xiaolong Wang 0004   +9 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Ex-PRESS Implantation versus Trabeculectomy for Long-Term Maintenance in Patients with Open-Angle Glaucoma

Clinical Ophthalmology, 2023
Kana Tokumo,1 Naoki Okada,1 Hiromitsu Onoe,1 Kaori Komatsu,1 Shun Masuda,1 Hideaki Okumichi,1 Kazuyuki Hirooka,1 Ryo Asaoka,2 Yoshiaki Kiuchi1 1Department of Ophthalmology and Visual Science, Hiroshima University Graduate School of Biomedical Sciences ...
Tokumo K, Okada N, Onoe H, Komatsu K, Masuda S, Okumichi H, Hirooka K, Asaoka R, Kiuchi Y   +8 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Predictive factors for visual prognosis in neurosyphilis presenting with optic atrophy: a Chinese case series study

Frontiers in Neurology
BackgroundWe aimed to explore the clinical features and predictive factors for visual prognosis of neurosyphilis-associated optic atrophy (NSAOA).MethodsThis retrospective observational study included 17 patients (33 eyes) with NSAOA who received ...
Mingjie Zhu, Xin Gu, Pingyu Zhou, Yan Yan   +3 more
doaj   +1 more source