Results 41 to 50 of about 67,497 (259)
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Bilateral permanent concentric visual field defect secondary to severe pre-eclampsia
Clinical Ophthalmology, 2008 Mehmet Citirik, Tulay Simsek, Orhan ZileliogluSB Ankara Ulucanlar Eye Education and Research Hospital, Ankara, TurkeyPurpose: To present a patient with bilateral permanent concentric visual field defect secondary to severe pre-eclampsia.Case report: A ...
Mehmet Citirik +2 more
doaj
Visual Field Loss Progression after Macular Hole Surgery
Journal of Ophthalmology, 2009 Purpose. To report a patient who experienced visual field loss progression after vitrectomy for an idiopathic stage II macular hole. Methods. Case report. A 68-year-old woman, with no history of glaucoma or any neuroophthalmological diseases, underwent a
Gian Marco Tosi +5 more
doaj +1 more source
Case Reports in Neurology, 2023 Posterior ischemic optic neuropathy (PION), a relatively rare condition, is diagnosed primarily based on the clinical presentation of sudden visual impairment, an optic nerve-related visual field defect, and an initial normal optic disc that corresponds ...
Cheng-En Wu +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Unusual presentation of a retrobulbar optic nerve sheath meningioma: a case report
Frontiers in NeurologyIntroductionWe report a case of a slowly progressive unilateral visual field defect associated with an atypical retrobulbar optic nerve sheath lesion in the context of concurrent breast cancer, which was ultimately diagnosed as meningothelial meningioma ...
Johannes Robert Fleischer +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Acute Zonal Occult Outer Retinopathy: Vision Loss in an Active Duty Soldier
Case Reports in Medicine, 2013 Objective. To describe a case of acute zonal occult outer retinopathy (AZOOR) in an active duty patient. Methods. In this paper we studied fundus photographs, optical coherence tomograph, Humphrey visual field 30-2, fundus autofluorescence images ...
Courtney M. Crawford +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Superior segmental optic nerve hypoplasia accompanied by progressive normal-tension glaucoma
Clinical Ophthalmology, 2012 Yoshio Yamazaki, Fukuko HayamizuDepartment of Ophthalmology, Division of Visual Science, Nihon University School of Medicine, Tokyo, JapanAbstract: This is the first case report of a superior segmental optic hypoplasia (SSOH) combined with normal-tension
Yamazaki Y, Hayamizu F
doaj