Results 61 to 70 of about 1,118,673 (315)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Diagnostic Accuracies of a Smartphone-Based Fundus Photography and Tablet-Based Visual Field Testing

Philippine Journal of Ophthalmology, 2022
Objective: We determined the diagnostic accuracies of the mydriatic, monoscopic, iPhone 6s+ optic nerve photographs with a 20D lens and the Melbourne Rapid Fields (MRF) visual fields iPad application.
Patricia Anne S. Tecson MD, MBA, Victor Jose L. Caparas MD, MPh, Rainier Victor A. Covar, MD, MMed   +2 more
doaj  

A Field Study of the Impact of Indoor Lighting on Visual Perception and Cognitive Performance in Classroom

Applied Sciences, 2020
In this field study, a series of psychophysical tests were conducted to investigate the impact of indoor lighting on students’ visual perception and cognitive performance.
Qiang Liu, Zheng Huang, Zhijiang Li, Michael R. Pointer, Geng Zhang, Zhen Liu, Hanwen Gong, Zhen Hou   +7 more
doaj   +1 more source

Association between visual field damage and corneal structural parameters

Scientific Reports, 2021
The main goal of this study is to identify the association between corneal shape, elevation, and thickness parameters and visual field damage using machine learning.
Alexandru Lavric, Valentin Popa, Hidenori Takahashi, Rossen M. Hazarbassanov, Siamak Yousefi   +4 more
doaj   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Spectroscopic determination of the fundamental parameters of 66 B-type stars in the field-of-view of the CoRoT satellite [PDF]

, 2009
We aim to determine the fundamental parameters of a sample of B stars with apparent visual magnitudes below 8 in the field-of-view of the CoRoT space mission, from high-resolution spectroscopy.
Aerts, Aerts, Briquet, C. Aerts, Decin, Desmet, Dufton, Dupret, Evans, Frémat, Gray, Gray, Gräfener, Handler, Hauschildt, Hempel, Hillier, Hubeny, Hubrig, Hubrig, Hunter, Hunter, Hunter, J. Puls, K. Lefever, Kudritzki, L. Decin, Lefever, Levenberg, M. Briquet, Maeder, Markova, Marquardt, Massey, Mazumdar, Miglio, Miglio, Mokiem, Morel, Morel, Morel, Morel, Neiner, Niemczura, Pauldrach, Przybilla, Puls, Puls, Repolust, Saio, Santolaya-Rey, Scuflaire, Simón-Díaz, Solano, T. Morel, Trundle, Vrancken   +56 more
core   +4 more sources

Log file‐based quality assurance method for respiratory gating system

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background As medical linear accelerator technology advances, enabling higher dose rate deliveries, hypofractionation regimens has increased. This necessitates respiratory gating systems that synchronize radiation delivery with tumor position, requiring simple rigorous quality assurance (QA) to ensure treatment accuracy and patient safety ...
Wonjoong Cheon, Young Kyu Lee, Yunji Seol, Chan‐beom Park, Hong Qi Tan, Kyu Hye Choi, Young‐nam Kang, Byung Ock Choi   +7 more
wiley   +1 more source

Evaluating feature extraction reproducibility across image biomarker standardization initiative‐compliant radiomics platforms using a digital phantom

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The aim of this study was to thoroughly analyze the reproducibility of radiomics feature extraction across three Image Biomarker Standardization Initiative (IBSI)‐compliant platforms using a digital phantom for benchmarking. It uncovers high consistency among common features while also pointing out the necessity for standardization ...
Han‐Back Shin, Heesoon Sheen, Jang‐Hoon Oh, Young Eun Choi, Kihoon Sung, Hyun Ju Kim   +5 more
wiley   +1 more source

Arteriovenous Passage Times and Visual Field Progression in Normal Tension Glaucoma

The Scientific World Journal, 2013
Purpose. Fluorescein angiographic studies revealed prolonged arteriovenous passage (AVP) times and increased fluorescein filling defects in normal tension glaucoma (NTG) compared to healthy controls.
Eva Charlotte Koch, Kay Oliver Arend, Marion Bienert, Andreas Remky, Niklas Plange   +4 more
doaj   +1 more source