Results 61 to 70 of about 2,804,631 (382)

Avoiding unseen obstacles : Subcortical vision is not sufficient to maintain normal obstacle avoidance behaviour during reaching [PDF]

open access: yes, 2016
Acknowledgement This work was funded by the RS MacDonald Charitable Trust (awarded to C. Hesse in June 2013). T. Schenk was supported by a grant from the German Research Council (DFG – SCHE 735/3-1).
Billino, Jutta   +4 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Spectroscopic determination of the fundamental parameters of 66 B-type stars in the field-of-view of the CoRoT satellite [PDF]

open access: yes, 2009
We aim to determine the fundamental parameters of a sample of B stars with apparent visual magnitudes below 8 in the field-of-view of the CoRoT space mission, from high-resolution spectroscopy.
Aerts   +56 more
core   +4 more sources

Longitudinal study of visual field changes determined by Humphrey Field Analyzer 10-2 in patients with Retinitis Pigmentosa

open access: yesScientific Reports, 2017
The aim of this study is to determine the progress of the visual field defects obtained by the Humphrey Field Analyzer 10-2 program (HFA 10-2) in patients with retinitis pigmentosa (RP). The medical records of 45 eyes of 45 RP patients who had at least 3
Akira Sayo   +10 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Data obtained with an open-source static automated perimetry test of the full visual field in healthy adults

open access: yesData in Brief, 2018
The data were gathered from 98 eyes of 98 ocular healthy subjects. The subject ages ranged from 18 to 79 years with a mean (and standard deviation) of 47 (17) years.
Iván Marín-Franch   +4 more
doaj   +1 more source

Ingested insecticide to control Aedes aegypti: developing a novel dried attractive toxic sugar bait device for intra-domiciliary control

open access: yes, 2020
© 2020 The Author(s). Background: Illnesses transmitted by Aedes aegypti (Linnaeus, 1762) such as dengue, chikungunya and Zika comprise a considerable global burden; mosquito control is the primary public health tool to reduce disease transmission ...
Aguirre, A.   +11 more
core   +2 more sources

Orientation of \u3ci\u3eHylobius Pales\u3c/i\u3e and \u3ci\u3ePachylobius Picivorus\u3c/i\u3e (Coleoptera: Curculionidae) to Visual Cues [PDF]

open access: yes, 2017
Pitfall traps with above-ground silhouettes of various colors and diameters were used in field tests to evaluate the role of vision in host orientation by adult pales weevils, Hylobius pales, and pitch-eating weevils, Pachylobius picivorus.
Hunt, D.W. A, Raffa, K. F
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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