Results 91 to 100 of about 352,043 (365)

Coordinated optimization of visual cortical maps : 2. Numerical studies

open access: yes, 2012
In the juvenile brain, the synaptic architecture of the visual cortex remains in a state of flux for months after the natural onset of vision and the initial emergence of feature selectivity in visual cortical neurons. It is an attractive hypothesis that
Heide, Dominik   +17 more
core   +1 more source

A biologically inspired spiking model of visual processing for image feature detection [PDF]

open access: yes, 2015
To enable fast reliable feature matching or tracking in scenes, features need to be discrete and meaningful, and hence edge or corner features, commonly called interest points are often used for this purpose.
Kerr, D   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Central Retinal Artery Occlusion After Nasosinal Surgery – an Insight

open access: yesInternational Medical Case Reports Journal, 2020
Somya Chowdhary,1 Vivek Sawhney,2 Abhijit Pandya,2 Kumar Sambhav,3 Shailesh K Gupta2 1Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA; 2Specialty Retina Centre, Coral Springs, FL, USA; 3Department of Ophthalmology, University of Florida,
Chowdhary S   +4 more
doaj  

Haptic glyphs (hlyphs) - structured haptic objects for haptic visualization [PDF]

open access: yes, 2005
Haptic devices can be used to visualize information. As well as representing tangible surfaces and forces to enhance virtual training simulators for instance, haptic devices have been used to realize tactile versions of diagrams and visualizations (such ...
K. Franklin   +3 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Does the World Health Organization criterion adequately define glaucoma blindness?

open access: yesClinical Ophthalmology, 2017
P Mokhles, JSAG Schouten, HJM Beckers, CAB Webers University Eye Clinic Maastricht, Maastricht, the Netherlands Purpose: Blindness in glaucoma is difficult to assess with merely the use of the current World Health Organization (WHO) definition (a ...
Mokhles P   +3 more
doaj  

Combining optical coherence tomography with visual field data to rapidly detect disease progression in glaucoma: a diagnostic accuracy study

open access: yesHealth Technology Assessment, 2018
Background: Progressive optic nerve damage in glaucoma results in vision loss, quantifiable with visual field (VF) testing. VF measurements are, however, highly variable, making identification of worsening vision (‘progression’) challenging. Glaucomatous
David F Garway-Heath   +7 more
doaj   +1 more source

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