Results 51 to 60 of about 1,309,431 (344)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Measurement of the hypotenuse of the vertical optic nerve head cup with spectral-domain optical coherence tomography for the structural diagnosis of glaucoma

Clinical Ophthalmology, 2018
Fabio Lavinsky,1,2 Camila Zanella Benfica,2 Nédio Castoldi,2 Anne Elise Cruz do Carmo Chaves,2 Paulo Augusto de Arruda Mello1 1Department of Ophthalmology, Paulista School of Medicine, São Paulo Hospital, Universidade Federal de São
Lavinsky F, Benfica CZ, Castoldi N, Cruz do Carmo Chaves AE, Mello PAA   +4 more
doaj  

Combining optical coherence tomography with visual field data to rapidly detect disease progression in glaucoma: a diagnostic accuracy study

Health Technology Assessment, 2018
Background: Progressive optic nerve damage in glaucoma results in vision loss, quantifiable with visual field (VF) testing. VF measurements are, however, highly variable, making identification of worsening vision (‘progression’) challenging. Glaucomatous
David F Garway-Heath, Haogang Zhu, Qian Cheng, Katy Morgan, Chris Frost, David P Crabb, Tuan-Anh Ho, Yannis Agiomyrgiannakis   +7 more
doaj   +1 more source

Profile of brain tumors having ocular manifestations in a Tertiary Eye Care Institute: A retrospective study

TNOA Journal of Ophthalmic Science and Research, 2018
Aim: To form a profile of brain tumors having ocular manifestations presenting to a tertiary eye care institute. Materials and Methods: The medical records of patients diagnosed with primary brain tumors between January 2012 and December 2017 were ...
Saurabh Deshmukh, Dipankar Das, Harsha Bhattacharjee, Ganesh Ch Kuri, Damaris Magdalene, Krati Gupta, Prabhjot Kaur Multani, Vivek Paulbuddhe, Shriya Dhar   +8 more
doaj   +1 more source

White-headed Vultures Trigonoceps occipitalis show visual field characteristics of hunting raptors [PDF]

, 2017
The visual fields of Aegypiinae vultures have been shown to be adapted primarily to meet two key perceptual challenges of their obligate carrion-feeding behaviour: scanning the ground and preventing the sun’s image falling upon the retina.
Fowler, Griffiths, Guillemain, Kane, Martin, Martin, Martin, Martin, Martin, Martin, Martin, Martin, Martin, Mundy, Mundy, Murn, O'Rourke, Potier   +17 more
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Visual Field Advantage: Redefined by Training?

Frontiers in Psychology, 2019
Previc (1990) postulated that most peri-personal space interactions occurred in the lower visual field (LVF), leading to an advantage when compared to the upper visual field (UVF).
Scott A. Stone, Jared Baker, Rob Olsen, Robbin Gibb, Jon Doan, Jon Doan, Joshua Hoetmer, Claudia L. R. Gonzalez, Claudia L. R. Gonzalez   +8 more
doaj   +1 more source

Visual acuity after trabeculectomy [PDF]

Vojnosanitetski Pregled, 2005
Background/Aim. In this study we compared the two groups of glaucoma patients who had underwent trabeculectomy, with or without intraoperative application of antimetabolite 5-Fluorouracile (5 FU). Methods. We followed up 50 glaucoma patients (group I) in
Buzarovska-Blaževska Karolina, Jordanova-Dimovska Vesna, Vukosavljević Miroslav, Džajkovska Elena   +3 more
doaj   +1 more source

Exocentric Pointing in the Visual Field [PDF]

i-Perception, 2013
“Exocentric pointing in the visual field” involves the setting of a pointer so as to visually point to a target, where both pointer and target are objects in the visual field. Phenomenologically, such pointings show systematic deviations from veridicality of several degrees.
Johan Wagemans, Jan J. Koenderink, Andrea J. van Doorn   +2 more
openaire   +5 more sources

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source