Results 51 to 60 of about 1,399,800 (288)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Measurement of the hypotenuse of the vertical optic nerve head cup with spectral-domain optical coherence tomography for the structural diagnosis of glaucoma

Clinical Ophthalmology, 2018
Fabio Lavinsky,1,2 Camila Zanella Benfica,2 Nédio Castoldi,2 Anne Elise Cruz do Carmo Chaves,2 Paulo Augusto de Arruda Mello1 1Department of Ophthalmology, Paulista School of Medicine, São Paulo Hospital, Universidade Federal de São
Lavinsky F, Benfica CZ, Castoldi N, Cruz do Carmo Chaves AE, Mello PAA   +4 more
doaj  

Correlation of diurnal fluctuations in intraocular pressure and progression of chronic simple glaucoma

Kerala Journal of Ophthalmology
Purpose: To study the correlation between diurnal fluctuations of intraocular pressure and progression of chronic simple glaucoma. Introduction: Out of all the risk factors for glaucoma, only modifiable risk factor is intraocular pressure.
Noorjahan Sajid, Priyangee Sen, Shoeb Mohd, Shrishti Ahuja   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Adding Genetics to the Risk Factors Model Improved Accuracy for Detecting Visual Field Progression in Newly Diagnosed Exfoliation Glaucoma Patients

Biomedicines
Background: This study aims to determine whether including genetics as a risk factor for progression will improve the accuracy of the models used in newly diagnosed exfoliation glaucoma patients. Methods: This was a prospective cohort study.
Marcelo Ayala
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Visual functions and their association with road traffic accidents among vehicle drivers in Gauteng

African Vision and Eye Health
Background: South Africa has a high mortality rate because of road traffic accidents (RTAs) compared to other countries. Aim: To determine the visual functions and their association with the occurrence of RTAs among vehicle drivers in the Gauteng ...
Gloria T. Tamenti, Tuwani A. Rasengane, Khathutshelo P. Mashige   +2 more
doaj   +1 more source

Acute Macular Neuroretinopathy Presenting as Bitemporal Defects on Humphrey Visual Field

Vision Pan-America, 2016
A 25-year-old woman presented with blurry vision, headache, nausea, and syncope. Humphrey visual field testing revealed bitemporal defects, but magnetic resonance imaging was negative for chiasmal pathology.
Rachel Mogil, Serena Fragiotta, Gaetano Barile, Jamie Mitchell   +3 more
doaj   +1 more source

Early Functional Connectivity Predicts Recovery from Visual Field Defects after Stroke [PDF]

Journal of Stroke, 2019
Background and Purpose We aimed to assess whether early resting-state functional connectivity (RSFC) changes measured via functional magnetic resonance imaging (fMRI) could predict recovery from visual field defect (VFD) in acute stroke patients. Methods
Yong-Hwan Kim, A-Hyun Cho, Dongho Kim, Seung Min Kim, Hyun Taek Lim, Sun U. Kwon, Jong S. Kim, Dong-Wha Kang   +7 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source