Results 91 to 100 of about 15,479,564 (391)

P336: Resolving missing heritability by iterative multidisciplinary and organ-specific reanalysis

Genetics in Medicine Open, 2023
Ehsan Ullah, Bin Guan, Amelia Naik, Chelsea Bender, Ranya Al Rawi, Delphine Blain, Aime Agather, Laryssa Huryn, Wadih Zein, Catherine Cukras, Brian Brooks, Robert Hufnagel   +11 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Ganoderma lucidum polysaccharide attenuates retinal ischemia-reperfusion injury by regulating microglial M1/M2 polarization, suppressing neuroinflammation and inhibiting JAK2/STAT3 pathway

Biochemistry and Biophysics Reports
Retinal ischemia-reperfusion (RIR) injury is implicated in the pathogenesis of numerous retinal degenerative disorders, resulting in visual impairment or even blindness in millions of individuals worldwide.
Guangyu Zhu, Yujie Liu, Shichun Luo, Chao Tang, Chunlin Zhao, Xuejing Lu   +5 more
doaj   +1 more source

The differential effects of lutein and zeaxanthin supplementation on myopia prevention in adolescents: a systematic review and Meta-analysis [PDF]

International Journal of Ophthalmology
AIM: To conduct a systematic review and Meta-analysis to determine the differential effects of combined lutein and zeaxanthin supplementation on myopia prevention in teenagers. It also investigates the effects of supplements dosage, intervention duration,
Li Pei, Ya Mo, Jun-Guo Duan
doaj   +1 more source

Discrete Multi-modal Hashing with Canonical Views for Robust Mobile Landmark Search

, 2017
Mobile landmark search (MLS) recently receives increasing attention for its great practical values. However, it still remains unsolved due to two important challenges.
He, Xiangnan, Huang, Zi, Liu, Xiaobai, Song, Jingkuan, Zhou, Xiaofang, Zhu, Lei   +5 more
core   +1 more source

Visual Function and Central Retinal Structure in Choroideremia.

Investigative Ophthalmology and Visual Science, 2016
PURPOSE To define the clinical phenotype of a cohort of patients affected with choroideremia. METHODS A retrospective study of patients with choroideremia included two centers. Data collected included age, visual acuity, refractive error, color vision,
E. Héon, Talal Alabduljalil, David B McGuigan Iii, A. Cideciyan, Shuning Li, Shiyi Chen, S. Jacobson   +6 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A systematic algorithm development for image processing feature extraction in automatic visual inspection : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in the Department of Production Technology, Massey University [PDF]

, 1990
Image processing techniques applied to modern quality control are described together with the development of feature extraction algorithms for automatic visual inspection.
Xing, G. X. (Guo Xin)
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The Diabetes Visual Function Supplement Study (DiVFuSS)

British Journal of Ophthalmology, 2015
Background Diabetes is known to affect visual function before onset of retinopathy (diabetic retinopathy (DR)). Protection of visual function may signal disruption of mechanisms underlying DR.
A. P. Chous, S. Richer, Jeffry D. Gerson, R. Kowluru, Dr A Paul Chous   +4 more
semanticscholar   +1 more source