Results 141 to 150 of about 15,479,564 (391)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Artemisinin and Its Derivatives: Promising Therapeutic Agents for Age-Related Macular Degeneration

Pharmaceuticals
Age-related macular degeneration (AMD) is a leading cause of visual impairment and blindness in older adults. Its pathogenesis involves multiple factors, including aging, environmental influences, genetic predisposition, oxidative stress, metabolic ...
Chun Liu, Xiaoqin Liu, Junguo Duan
doaj   +1 more source

Vision science and technology for supervised intelligent space robots [PDF]

The focus of recent work in robotic vision for application in intelligent space robots such as the Extravehicular Activity (EVA) Retriever is in visual function, that is, how information about the space world is derived and then conveyed to cognition ...
Erickson, Jon D.
core   +1 more source

Importance of Pattern Standard Deviation of Humphrey 10-2 Visual Field to Evaluate Central Visual Function in Patients with Early-Stage Glaucoma [PDF]

, 2023
Hee Jong Shin, Si Eun Oh, Chan Kee Park, Hae-Young Lopilly Park   +3 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Prediction of myopia based on biometric parameters of 500,000 children and adolescents aged 3–18 years

Frontiers in Public Health
PurposeTo explore the validity and significance of the axial length/corneal radius (AL/CR) Ratio for myopia prediction in children of all ages.MethodsBetween 2020 and 2022, 509,530 children and adolescents aged 3–18 years were sampled in Chengdu City ...
Siyu Chen, Siyu Chen, Siyu Chen, Siyu Chen, Jingyu Mu, Jingyu Mu, Jingyu Mu, Jingyu Mu, Xiyue Tan, Xiyue Tan, Xiyue Tan, Xiyue Tan, Xiaoxiao Wu, Xiaoxiao Wu, Xiaoxiao Wu, Junguo Duan, Junguo Duan, Junguo Duan, Junguo Duan   +18 more
doaj   +1 more source

Threshold exposure duration as a function of luminance for visual recognition [PDF]

, 1969
Katherine E. Baker
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Beyond visual acuity: Patient-relevant assessment measures of visual function in retinal diseases

, 2021
María C. Puell, Inés Contreras, Isabel Pinilla, José J. Escobar, Antonio Soler-García, Antonio Javier Blasco, Pablo Lázaro   +6 more
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source