Results 21 to 30 of about 3,231,328 (345)

Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation

open access: yesEpigenetics & Chromatin, 2022
Background Methylation at cytosines (mCG) is a well-known regulator of gene expression, but its requirements for cellular differentiation have yet to be fully elucidated. A well-studied cellular differentiation model system is the eye lens, consisting of
Joshua Disatham   +5 more
doaj   +1 more source

Retinal Development and Pathophysiology in Kcnj13 Knockout Mice

open access: yesFrontiers in Cell and Developmental Biology, 2022
Purpose: We constructed and characterized knockout and conditional knockout mice for KCNJ13, encoding the inwardly rectifying K+ channel of the Kir superfamily Kir7.1, mutations in which cause both Snowflake Vitreoretinal Degeneration (SVD) and Retinitis
Xiaodong Jiao   +10 more
doaj   +1 more source

Visual feedback alters force control and functional activity in the visuomotor network after stroke. [PDF]

open access: yes, 2018
Modulating visual feedback may be a viable option to improve motor function after stroke, but the neurophysiological basis for this improvement is not clear.
Archer, Derek B   +5 more
core   +2 more sources

Visual Acuity does not Moderate Effect Sizes of Higher-Level Cognitive Tasks. [PDF]

open access: yes, 2016
Background/study contextDeclining visual capacities in older adults have been posited as a driving force behind adult age differences in higher-order cognitive functions (e.g., the "common cause" hypothesis of Lindenberger & Baltes, 1994, Psychology ...
Allen, Philip A   +3 more
core   +2 more sources

Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb deletion in the OCA2 gene revealed a co-segregation of the controversial variant, p.R305W

open access: yesCell & Bioscience, 2017
Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant either in the TYR or the OCA2 gene.
Jackson Gao   +7 more
doaj   +1 more source

Time-locked perceptual fading induced by visual transients [PDF]

open access: yes, 2003
After prolonged fixation, a stationary object placed in the peripheral visual field fades and disappears from our visual awareness, especially at low luminance contrast (the Troxler effect).
Kamitani, Yukiyasu, Kanai, Ryota
core   +2 more sources

Bibliometric Analysis of Artificial Intelligence in Diabetic Retinopathy [PDF]

open access: yesZhongguo quanke yixue, 2023
Background In recent years, artificial intelligence (AI) has shown rapid development in the medical field, and its application in diabetic retinopathy (DR) has been expanding.
LIU Chun, JIAN Wenyuan, DUAN Junguo
doaj   +1 more source

Improving visual functions in adult amblyopia with combined perceptual training and transcranial random noise stimulation (tRNS): a pilot study [PDF]

open access: yes, 2014
Amblyopia is a visual disorder due to an abnormal pattern of functional connectivity of the visual cortex and characterized by several visual deficits of spatial vision including impairments of visual acuity (VA) and of the contrast sensitivity function (
Astle   +41 more
core   +2 more sources

Regulatory considerations for developing a phase I investigational new drug application for autologous induced pluripotent stem cells‐based therapy product

open access: yesStem Cells Translational Medicine, 2021
Induced pluripotent stem cells (iPSC)‐based therapies have been hailed as the future of regenerative medicine because of their potential to provide treatment options for most degenerative diseases. A key promise of iPSC‐based therapies is the possibility
Balendu Shekhar Jha   +2 more
doaj   +1 more source

Quality of life and visual function in Nigeria: findings from the National Survey of Blindness and Visual Impairment [PDF]

open access: yes, 2011
Aims To assess associations of visual function (VF) and quality of life (QOL) by visual acuity (VA), causes of blindness and types of cataract procedures in Nigeria. Methods Multi-stage stratified cluster random sampling was used to identify a nationally
Abubakar, T   +10 more
core   +1 more source

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