Results 21 to 30 of about 3,248,315 (198)

Regulatory considerations for developing a phase I investigational new drug application for autologous induced pluripotent stem cells‐based therapy product

open access: yesStem Cells Translational Medicine, 2021
Induced pluripotent stem cells (iPSC)‐based therapies have been hailed as the future of regenerative medicine because of their potential to provide treatment options for most degenerative diseases. A key promise of iPSC‐based therapies is the possibility
Balendu Shekhar Jha   +2 more
doaj   +1 more source

The cognitive neuroscience of visual working memory [PDF]

open access: yes, 2017
Visual working memory allows us to temporarily maintain and manipulate visual information in order to solve a task. The study of the brain mechanisms underlying this function began more than half a century ago, with Scoville and Milner’s (1957) seminal ...
Kaldy, Zsuzsa, Sigala, Natasha
core   +1 more source

Visual Acuity does not Moderate Effect Sizes of Higher-Level Cognitive Tasks. [PDF]

open access: yes, 2016
Background/study contextDeclining visual capacities in older adults have been posited as a driving force behind adult age differences in higher-order cognitive functions (e.g., the "common cause" hypothesis of Lindenberger & Baltes, 1994, Psychology ...
Allen, Philip A   +3 more
core   +2 more sources

Rod and Cone Coupling Modulates Photopic ERG Responses in the Mouse Retina

open access: yesFrontiers in Cellular Neuroscience, 2020
Light adaptation changes both the sensitivity and maximum amplitude (Rmax) of the mouse photopic electroretinogram (ERG) b-wave. Using the ERG, we examined how modulation of gap junctional coupling between rod and cones alters the light-adapted ERG.
Yichao Li, Ethan D. Cohen, Haohua Qian
doaj   +1 more source

Visual feedback alters force control and functional activity in the visuomotor network after stroke. [PDF]

open access: yes, 2018
Modulating visual feedback may be a viable option to improve motor function after stroke, but the neurophysiological basis for this improvement is not clear.
Archer, Derek B   +5 more
core   +2 more sources

CLCC1 c. 75C>A Mutation in Pakistani Derived Retinitis Pigmentosa Families Likely Originated With a Single Founder Mutation 2,000–5,000 Years Ago

open access: yesFrontiers in Genetics, 2022
Background: A CLCC1 c. 75C > A (p.D25E) mutation has been associated with autosomal recessive pigmentosa in patients in and from Pakistan. CLCC1 is ubiquitously expressed, and knockout models of this gene in zebrafish and mice are lethal in the ...
Yan Ma   +18 more
doaj   +1 more source

Research Progress of Ocular Glymphatic System and Related Ocular Diseases [PDF]

open access: yesZhongguo quanke yixue, 2023
Recent discovered ocular glymphatic system, which is facilitated by aquaporin-4 (AQP4) and dependent on the exchange system of aqueous humor-tissue fluid in the perivascular space of retinal arterial and venous, ultimately acts as the role of expelling ...
ZHU Guangyu, CHENG Yuxin, LU Xuejing
doaj   +1 more source

Thalamic regulation of ocular dominance plasticity in adult visual cortex

open access: yeseLife, 2023
Experience-dependent plasticity in the adult visual system is generally thought of as a cortical process. However, several recent studies have shown that perceptual learning or monocular deprivation can also induce plasticity in the adult dorsolateral ...
Yi Qin   +6 more
doaj   +1 more source

Is there overutilisation of cataract surgery in England? [PDF]

open access: yes, 2009
<b>Objectives:</b> Following a 3.7-fold increase in the rate of cataract surgery in the UK between 1989 and 2004, concern has been raised as to whether this has been accompanied by an excessive decline in the threshold such that some ...
Black, N.   +5 more
core   +1 more source

A novel LRAT mutation affecting splicing in a family with early onset retinitis pigmentosa

open access: yesHuman Genomics, 2018
Background and purpose Retinitis pigmentosa is an important cause of severe visual dysfunction. This study reports a novel splicing mutation in the lecithin retinol acyltransferase (LRAT) gene associated with early onset retinitis pigmentosa and ...
Yabin Chen   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy