Results 71 to 80 of about 273,835 (294)
A Multimodal Discourse Analysis of Aircraft Cabin Safety Briefing Card: A Visual Grammar Approach
Insights into Language, Culture and CommunicationCabin safety briefing cards are informative texts and pictograms that provide detailed explanations of aircraft safety features, equipment usage, and procedures. They play a crucial role in cabin safety management.
Wen Zhao
doaj +1 more source
Design synthesis and shape generation [PDF]
, 2009 If we are to capitalise on the potential that a design approach might bring to innovation in business and society, we need to build a better understanding of the evolving skill-sets that designers will need and the contexts within which design might ...
AHRC (Funder) +11 more
core +1 more source
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
Advanced Science, EarlyView.This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
"Mind your p's and q's": or the peregrinations of an apostrophe in 17th Century English
, 2009 If the use of the apostrophe in contemporary English often marks the Saxon genitive, it may also indicate the omission of one or more let-ters. Some writers (wrongly?) use it to mark the plural in symbols or abbreviations, visual-ised thanks to the ...
Pignot, Hélène, Piton, Odile
core +2 more sources
Advanced Science, EarlyView.We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua +6 more
wiley +1 more source
gMotion: A spatio-temporal grammar for the procedural generation of motion graphics [PDF]
, 2018 Creating by hand compelling 2D animations that choreograph several groups of shapes requires a large number of manual edits. We present a method to procedurally generate motion graphics with timeslice grammars.
Carra, Edoardo +2 more
core
The Polymers of Life: Exploring Cellular Function Through Polymer Concepts
Advanced Science, EarlyView.Biomolecular phase separation reveals that a hidden layer of cellular organization is governed by the principles of polymer science. This review bridges polymer physics and cell biology, offering a primer on fundamental concepts, proposing a framework for interrogating cellular function, and synthesizing biophysical methods for decoding macromolecular ...
Mark Chen, Ashutosh Chilkoti
wiley +1 more source
A CNL for Contract-Oriented Diagrams
, 2014 We present a first step towards a framework for defining and manipulating normative documents or contracts described as Contract-Oriented (C-O) Diagrams.
C. Prisacariu +6 more
core +1 more source
Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy
Advanced Science, EarlyView.ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang +10 more
wiley +1 more source
MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes
Advanced Science, EarlyView.A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak +19 more
wiley +1 more source