Results 91 to 100 of about 2,240,353 (293)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Visual images of Palestine on the pages of pilgrimage texts of the late 19th and early 20th centuries / Визуальные образы Палестины на страницах паломнических текстов конца XIX – начала XX вв.

open access: yesВизуальная теология
The article is devoted to the study of visual images presented in texts devoted to pilgrimage to Palestine of the late 19th – early 20th century. The research interest is based on the idea of illustration as a way of overcoming the rationality of ...
Alexander Valitov / Александр Александрович Валитов
doaj   +1 more source

VISUAL CULTURE AS A MEANS OF FORMING A COMMON AND PROFESSIONAL CULTURE OF A PERSON

open access: yesВестник Мининского университета, 2018
Introduction. The article is devoted to the analysis of the visual culture, which forms the general and professional culture of a person in many ways. Attention is paid to the culture of perception of visual images, the ability to analyze them, evaluate,
N. V. Syrova, V. N. Chikishev
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

The sense, landscape and image. How the tourist destination is replicated in postmodernist times

open access: yesPASOS Revista de Turismo y Patrimonio Cultural, 2013
Policy makers, practitioners and analysts have focused on the psychology to induce consumers to new products. These new eyecatching packaging products in tourism and hospitality industries and beyond are commercialized to thousands of home thanks to the
Maximiliano E. Korstanje
doaj   +1 more source

The brain-inspired decoder for natural visual image reconstruction. [PDF]

open access: yesFront Neurosci, 2023
Li W   +7 more
europepmc   +1 more source

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