Results 41 to 50 of about 771,460 (318)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The Topographic Relationships and Geographic Distribution of Prevascular Vitreous Fissures and Cisterns Assessed by Ultrawidefield En Face Vitreous Images

Ophthalmology Science
Purpose: To determine the topographic relationships and geographic distribution of prevascular vitreous fissures (PVFs) and cisterns across the entire posterior vitreous membrane in healthy subjects, using ultrawidefield en face and cross-sectional swept-
Fei Deng, MD, Mengying Tao, MD, Yanjie Zhu, MD, Xiaoyu Xu, MD, Yue Wu, MD, Lisha Li, Ying Lin, MD, PhD, Yan Luo, MD, PhD   +7 more
doaj   +1 more source

Image of Higher Educational Institutions: Features of Perception by Graduating Class Students

Высшее образование в России, 2023
The article is devoted to the problem of forming the image of higher educational institutions in the conditions of increasing competition in the regional market of educational services, as well as between regional and metropolitan educational ...
V. A. Sagaidak, A. L. Kuzevanova, O. Yu. Yabloskikh   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Bidirectional Transmission Mapping of Architectural Styles of Tibetan Buddhist Temples in China from the 7th to the 18th Century

Religions
Architecture is the stone book of history, and the evolution of architectural styles showcases a non-verbal history constructed through images. As an important part of China’s historical and cultural heritage, the architectural forms and styles of ...
Tianyi Min, Tong Zhang
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Automated Detection and Biomarker Identification Associated with the Structural and Functional Progression of Glaucoma on Longitudinal Color Fundus Images

Applied Sciences
The diagnosis of primary open-angle glaucoma (POAG) progression based on structural imaging such as color fundus photos (CFPs) is challenging due to the limited number of early biomarkers, as commonly determined by clinicians, and the inherent ...
Iyad Majid, Zubin Mishra, Ziyuan Chris Wang, Vikas Chopra, Dale Heuer, Zhihong Jewel Hu   +5 more
doaj   +1 more source

Study on the Method of Matched Splice Grafting for Melon Seedlings Based on Visual Image

Agriculture, 2022
Due to the cutting mechanism of the existing grafting machine, it cannot adjust the cutting angle in real time, resulting in low fitting precision on the cutting surfaces between the rootstocks and scion seedlings and, thus, seriously affecting the ...
Pengyun Xu, Tong Zhang, Liping Chen, Wenqian Huang, Kai Jiang   +4 more
doaj   +1 more source