Results 81 to 90 of about 2,240,353 (293)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
THE ECONOMIC AND SOCIAL EFFECTS OF DRUG USE [PDF]
Annals of the University of Petrosani: Economics, 2019 The central concept of the study is communication, a symbolic communication due to the fact that although it is used by the same "paths" to communicate, it is actually about communicating a particular message through advertising posters. For extending to
COSMIN SERGIU CREMENE
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Visual Image Kartun Benny & Mice Versi Bluetooth Handsfree Representasi Kaum Miskin Kota Jakarta
Nirmana, 2009 Cartoon as a medium has made visualization one of most important points in transmitting messages as texts, whether verbal or visual, as a process of communication that generates meanings.
Deddi Duto Hartanto
doaj
Design considerations for a space database [PDF]
Part of the information used in a real-time simulator is stored in the visual database. This information is processed by an image generator and displayed as a real-time visual image.
Moss, Lance M.
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Souvenir design as a representation of the visual image of the urban space
Управление культурой, 2023 Relevance. Ekaterinburg pays a lot of attention to creating its own unique visual image. The easiest way to embody the visual image of the city is a souvenir.
Irina B. Bosykh
doaj
Visual saliency in noisy images
Journal of Vision, 2013 The human visual system possesses the remarkable ability to pick out salient objects in images. Even more impressive is its ability to do the very same in the presence of disturbances. In particular, the ability persists despite the presence of noise, poor weather, and other impediments to perfect vision.
Chelhwon, Kim, Peyman, Milanfar
openaire +2 more sources