Results 71 to 80 of about 2,372,548 (204)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The Effect of Internal and external imagery on learning badminton long serve skill: The role of visual and audiovisual imagery.

PLoS ONE
This study aimed to examine the impact of internal and external audiovisual imagery on the learning of the badminton long serve skill. A lot of 42 right-handed novice women were selected using availability sampling.
Fateme Parimi, Behrouz Abdoli, Hesam Ramezanzade, Mahin Aghdaei   +3 more
doaj   +1 more source

Distinct Top-down and Bottom-up Brain Connectivity During Visual Perception and Imagery

Scientific Reports, 2017
Research suggests that perception and imagination engage neuronal representations in the same visual areas. However, the underlying mechanisms that differentiate sensory perception from imagination remain unclear.
N. Dijkstra, P. Zeidman, S. Ondobaka, M. A. J. van Gerven, K. Friston   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Neural network topologies supporting individual variations in vividness of visual imagery

NeuroImage
Vividness of visual imagery varies considerably across individuals, yet its neural underpinnings remain unclear. As emphasized in recent debates, a key controversy is whether early sensory architecture explains imagery or whether it is explained by ...
Timo L. Kvamme, Massimo Lumaca, Claude J. Bajada, Signe Dall Gregersen, Justyna Hobot, Dunja Paunovic, Michal Wierzchon, Blanka Zana, Juha Silvanto, Kristian Sandberg   +9 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Imagery in Song Lyrics of Taylor Swift

Lingua: Jurnal Bahasa, Sastra dan Pengajarannya, 2020
The purposes of this research are to identify the kind of imagery in Taylor Swift song lyrics, how Taylor Swift describes imagery in her song lyrics, and dominant imagery in Taylor Swift song lyrics.
Unpris Yastanti, Susilawati Susilawati
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

The Pupillary Response in Visual Imagery

, 2022
Background: In recent years, there have been objective ways of investigations that examine the neural substrates and mechanisms of visual imagery. One of the studies adopted the pupillary light response to detecting the sensory strength and subjective ...
Sin Wan Sharon Hon, Sing-Hang Cheung
core   +1 more source