Results 51 to 60 of about 69,787 (300)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Reasoning, models, and images: behavioral measures and cortical activity

, 2003
The goal of this study was to investigate the neurocognitive processes of mental imagery in deductive reasoning. Behavioral studies yielded four sorts of verbal relations: (1) visuospatial relations that are easy to envisage both visually and spatially; (
Johnson Laird, PN, Knauff, Markus, Fangmeier, Thomas, Johnson-Laird, P., Knauff, M., Ruff, C., Fangmeier , T., Ruff, Christian C., Fangmeier, T, Ruff, CC, Knauff, M, Johnson-Laird, Philip N.   +11 more
core   +1 more source

Spatiotemporal dynamics of self-generated imagery reveal a reverse cortical hierarchy from cue-induced imagery

Cell Reports, 2023
Summary: Visual imagery allows for the construction of rich internal experience in our mental world. However, it has remained poorly understood how imagery experience derives volitionally as opposed to being cue driven. Here, using electroencephalography
Yiheng Hu, Qing Yu
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The effects of graded motor imagery and its components on chronic pain: A systematic review and meta-analysis [PDF]

, 2013
This is the post-print version of the final paper published in The Journal of Pain. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting ...
Leake, Hayley B., Chalmers, Jane (R18426), Stanton, Tasha R., O'Connell, Neil E., Catley, Mark J., Moseley, GL, Hayley B. Leake, O'Connell, NE, Neil E. O'Connell, Moseley, G.L., Mark J. Catley, Abby Tabor, Tabor, Abby, Catley, MJ, Bowering, K. Jane, Tabor, A, Moseley, G. Lorimer, Stanton, N.R., Stanton, TR, Leake, HB, Leake, H.B., G. Lorimer Moseley, Catley, M.J., K. Jane Bowering, Bowering, K.J., Tabor, A., Tasha R. Stanton, O'Connell, N.E.   +27 more
core   +1 more source

The effects of kinesthetic and visual motor imagery on interjoint coordination in the hemiplegic index finger: an experimental study using the index of temporal coordination

Cadernos Brasileiros de Terapia Ocupacional, 2021
Upper limb hemiparesis is a common impairment following stroke and can affect interjoint coordination. Motor imagery training is one treatment strategy. However, motor imagery can use visual or kinesthetic modalities and there has been a lack of research
Jonathon O’Brien, Robert Martyn Bracewell, Juan Alberto Castillo   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The mind's eye in blindfold chess

, 2005
Visual imagery plays an important role in problem solving, and research into blindfold chess has provided a wealth of empirical data on this question. We show how a recent theory of expert memory (the template theory, Gobet & Simon, 1996, 2000) accounts ...
Gobet, F., Campitelli, G., Campitelli, G, Gobet, F   +3 more
core   +1 more source

My hand or yours? Markedly different sensitivity to egocentric and allocentric views in the hand laterality task [PDF]

, 2011
In the hand laterality task participants judge the handedness of visually presented stimuli – images of hands shown in a variety of postures and views - and indicate whether they perceive a right or left hand.
Corrina Maguinness, Ní Choisdealbha, Á., Ni Choisdealbha, Aine, Brady, N., Maguinness, C., Brady, Nuala, Ní Choisdealbha Áine, Brady Nuala, Aine Ní Choisdealbha, Maguinness Corrina, Nuala Brady, Maguinness, Corrina   +11 more
core   +1 more source