Results 81 to 90 of about 69,787 (300)

Investigating visual analogies for visual insight problems [PDF]

open access: yes, 2010
Much research has focused on the impact of analogies in insight problem solving, but less work has investigated how the visual analogies for insight are actually constructed.
Luchian, Eric, Sas, Corina, Ball, Linden
core  

Neural network topologies supporting individual variations in vividness of visual imagery

open access: yesNeuroImage
Vividness of visual imagery varies considerably across individuals, yet its neural underpinnings remain unclear. As emphasized in recent debates, a key controversy is whether early sensory architecture explains imagery or whether it is explained by ...
Timo L. Kvamme   +9 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Neural activation and functional connectivity during motor imagery of bimanual everyday actions [PDF]

open access: yes, 2012
Bimanual actions impose intermanual coordination demands not present during unimanual actions. We investigated the functional neuroanatomical correlates of these coordination demands in motor imagery (MI) of everyday actions using functional magnetic ...
Sterr, A   +16 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Visual Imagery Facilitates Visual Perception: Psychophysical Evidence [PDF]

open access: yes, 1997
Visual imagery is the invention or recreation of a perceptual experience in the absence of retinal input.The degree to which the same neural representations are involved in both visual imagery and visual perception is unclear. Previous studies have shown
Ishai, A, Sagi, D
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Psychophysiological correlates of dynamic imagery [PDF]

open access: yes
Dynamic imagery refers both to the imaginary transformation of objects and to the imagination of bodily movements. It is hypothesised that dynamic imagery involves both motoric and visuo-spatial representations and to demonstrate that they operate at the
Williams, John Denzil
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Partial dissociation in the neural bases of VSTM and imagery in the early visual cortex [PDF]

open access: yes, 2015
Visual short-term memory (VSTM) and visual imagery are believed to involve overlapping neuronal representations in the early visual cortex. While a number of studies have provided evidence for this overlap, at the behavioral level VSTM and imagery are ...
Saad, Elyana   +5 more
core   +1 more source

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