Results 101 to 110 of about 4,218,690 (285)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Operability Improvement of Human-Machine Systems by Altering Visual Information: A Case-Study of the Inverted Pendulum

open access: yesIEEE Access
When humans operate machines such as cars and drones based on visual information, it is essential to improve the subjective operational feeling, avoid failures, and reduce the learning time, in other words, to improve operability.
Kenta Tanaka   +2 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

The Optimization of PID Controller and Color Filter Parameters with a Genetic Algorithm for Pineapple Tracking Using an ROS2 and MicroROS-Based Robotic Head

open access: yesComputation
This work proposes a vision system mounted on the head of an omnidirectional robot to track pineapples and maintain them at the center of its field of view. The robot head is equipped with a pan–tilt unit that facilitates dynamic adjustments.
Carolina Maldonado-Mendez   +4 more
doaj   +1 more source

The Role of Landscapes and Landmarks in Bee Navigation: A Review

open access: yesInsects, 2019
The ability of animals to explore landmarks in their environment is essential to their fitness. Landmarks are widely recognized to play a key role in navigation by providing information in multiple sensory modalities. However, what is a landmark?
Bahram Kheradmand, James C. Nieh
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

How far along the future path do individuals recognize the path for stepping on multiple footfall targets? A new evaluation method under virtual reality

open access: yesFrontiers in Sports and Active Living
IntroductionThe ability to visually recognize the path ahead during walking is essential for adjusting gait patterns in an anticipatory manner to mitigate perturbations induced by tripping.
Ryotaro Waki   +7 more
doaj   +1 more source

Separate cortical stages in amodal completion revealed by functional magnetic resonance adaptation : research article [PDF]

open access: yes, 2007
Background Objects in our environment are often partly occluded, yet we effortlessly perceive them as whole and complete. This phenomenon is called visual amodal completion. Psychophysical investigations suggest that the process of completion starts from
Muckli, Lars   +2 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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