Results 71 to 80 of about 4,218,690 (285)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

For efficient navigational search, humans require full physical movement but not a rich visual scene [PDF]

open access: yes, 2006
During navigation, humans combine visual information from their surroundings with body-based information from the translational and rotational components of movement.
Lessels, S., Ruddle, R.A.
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Visual Information Retrieval in Digital Libraries [PDF]

open access: yes, 1997
The emergence of information highways and multimedia computing has resulted in redefining the concept of libraries. It is widely believed that in the next few years, a significant portion of information in libraries will be in the form of multimedia ...
Jain, Ramesh
core  

Occlusion-related lateral connections stabilize kinetic depth stimuli through perceptual coupling [PDF]

open access: yes, 2009
Local sensory information is often ambiguous forcing the brain to integrate spatiotemporally separated information for stable conscious perception. Lateral connections between clusters of similarly tuned neurons in the visual cortex are a potential ...
Holten, Vivian   +4 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

AI nutrition recommendation using a deep generative model and ChatGPT

open access: yesScientific Reports
In recent years, major advances in artificial intelligence (AI) have led to the development of powerful AI systems for use in the field of nutrition in order to enhance personalized dietary recommendations and improve overall health and well-being ...
Ilias Papastratis   +3 more
doaj   +1 more source

Visual information seeking on palmtop devices [PDF]

open access: yes, 2000
Ahlberg and Shneiderman's Starfield displays have been shown to provide fast and convenient access to large collections of data. However, the standard design requires a large, high-resolution, colour screen.
Davidson, N., Dunlop, M.D.
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

PDualNet: a deep learning framework for joint prediction of Parkinson’s disease progression subtype and MDS-UPDRS scores

open access: yesScientific Reports
Parkinson’s disease is one of the most common and complex neurodegenerative diseases, characterized by remarkable motor and cognitive decline. As it is a highly heterogeneous disorder, i.e., the specific symptoms, their severity, and their progression ...
Vasiliki Rizou   +3 more
doaj   +1 more source

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