Results 81 to 90 of about 4,210,540 (287)

PDualNet: a deep learning framework for joint prediction of Parkinson’s disease progression subtype and MDS-UPDRS scores

Scientific Reports
Parkinson’s disease is one of the most common and complex neurodegenerative diseases, characterized by remarkable motor and cognitive decline. As it is a highly heterogeneous disorder, i.e., the specific symptoms, their severity, and their progression ...
Vasiliki Rizou, Nikos Grammalidis, Petros Daras, Kosmas Dimitropoulos   +3 more
doaj   +1 more source

A global decision-making model via synchronization in macrocolumn units [PDF]

, 2009
Poster presentation: Introduction We here address the problem of integrating information about multiple objects and their positions on the visual scene.
Burwick, Thomas, Jitsev, Evgueni, Malsburg, Christoph von der, Sato, Yasuomi D.   +3 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The CLAIRE visual analytics system for analysing IR evaluation data [PDF]

, 2018
In this paper, we describe Combinatorial visuaL Analytics system for Information Retrieval Evaluation (CLAIRE), a Visual Analytics (VA) system for exploring and making sense of the performances of a large amount of Information Retrieval (IR) systems, in ...
Angelini, Marco, Fazzini, Vanessa, Ferro, Nicola, Santucci, Giuseppe, Silvello, Gianmaria   +4 more
core  

Visual-Inertial Mapping with Non-Linear Factor Recovery

, 2020
Cameras and inertial measurement units are complementary sensors for ego-motion estimation and environment mapping. Their combination makes visual-inertial odometry (VIO) systems more accurate and robust.
Cremers, Daniel, Demmel, Nikolaus, Schubert, David, Stückler, Jörg, Usenko, Vladyslav   +4 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

IPD-Brain: An Indian histopathology dataset for glioma subtype classification

Scientific Data
The effective management of brain tumors relies on precise typing, subtyping, and grading. We present the IPD-Brain Dataset, a crucial resource for the neuropathological community, comprising 547 high-resolution H&E stained slides from 367 patients for ...
Ekansh Chauhan, Amit Sharma, Megha S. Uppin, Manasa Kondamadugu, C. V. Jawahar, P. K. Vinod   +5 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source