Results 201 to 210 of about 664,902 (268)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Through the fog: Systematic review and meta-analysis of the prevalence and associated factors of poor post-operative visual outcome of cataract surgery in Sub-Saharan Africa. [PDF]

PLoS One
Asmare ZA, Seifu BL, Fente BM, Negussie YM, Asebe HA, Bezie MM, Melkam M, Asnake AA.   +7 more
europepmc   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Visual outcome of various dose of glucocorticoids treatment in nonarteritic anterior ischemic optic neuropathy- a retrospective analysis. [PDF]

BMC Ophthalmol
Zhao FF, Chen Y, Li TP, Wang Y, Lin HJ, Yang JF, Chen L, Tan SY, Liang JJ, Cen LP.   +9 more
europepmc   +1 more source

Topical NSAIDs impact on macular oedema and visual outcome after phacoemulsification: systematic review of RCTs with network meta-analysis. [PDF]

Eye (Lond)
Almasri M, Ismaiel A, Gavris I, Leucuta DC, Gavris MM, Nicoara SD.   +5 more
europepmc   +1 more source

Effects of Lotrafilcon A and Senofilcon A Bandage Contact Lenses on Visual Outcome and Ocular Comfort After Photorefractive Keratectomy. [PDF]

Turk J Ophthalmol
Yakar K, Alaçamlı G.
europepmc   +1 more source

Visual Outcome of Nontraumatic Dense Vitreous Hemorrhage in Patients without Diabetes: A Single-Center Case Series. [PDF]

Korean J Ophthalmol
Lee Y, Kim JS.
europepmc   +1 more source

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Visual outcomes in corneal transplantation

British Journal of Ophthalmology, 2012
▸  Related article: 10.1136/bjophthalmol-2011-301349 Penetrating keratoplasty (PK) or full thickness corneal transplantation has enjoyed great success for over a century.1 ,2 Dramatic visual improvement can be achieved by this procedure but it is not without problems.
Uday Kumar, Bhatt, Lana Akram, Faraj, Virinder, Dhillon, Harminder Singh, Dua   +3 more
openaire   +2 more sources