Results 61 to 70 of about 757,076 (313)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
A biologically inspired spiking model of visual processing for image feature detection [PDF]
, 2015 To enable fast reliable feature matching or tracking in scenes, features need to be discrete and meaningful, and hence edge or corner features, commonly called interest points are often used for this purpose.
Kerr, D +3 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
PlantsAccurate light simulations using virtual plant models are essential for analyzing how plant structures influence the micro-light climate within canopies.
Jens Balasus +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
When Does Directional Reflectance Matter? Evaluating BRDF Effects in Plant Canopy Light Simulations
PlantsVirtual plant models combined with ray-tracing simulations are an established tool for evaluating plant–light interactions. Current approaches often simplify leaf surface properties by assuming diffuse reflectance behavior, despite experimental evidence ...
Jens Balasus +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Visual processing: The Devil is in the details [PDF]
Current Biology, 2000 Ganglion cells convey information from the retina back to the brain. Recent experiments have examined how ganglion cell receptive fields are assembled from many incoming signals.
Neves, Guilherme, Lagnado, Leon
openaire +2 more sources
A Co-Point Mapping-Based Approach to Drivable Area Detection for Self-Driving Cars
Engineering, 2018 The randomness and complexity of urban traffic scenes make it a difficult task for self-driving cars to detect drivable areas. Inspired by human driving behaviors, we propose a novel method of drivable area detection for self-driving cars based on fusing
Ziyi Liu, Siyu Yu, Nanning Zheng
doaj +1 more source
Brain and Behavior, 2023 Background and Purpose Many patients with chronic pain report hypersensitivity not only to noxious stimuli, but also to other modalities including innocuous touch, sound, and light, possibly due to differences in the processing of these stimuli. The goal
Daniel E. Harper +9 more
doaj +1 more source