Results 71 to 80 of about 389,716 (261)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Effect of premenstrual tension on audiovisual reaction time

open access: yesMRIMS Journal of Health Sciences, 2015
Background: Premenstrual tension has been known since long to affect the behavioural and physical well being of women. Behavioural differences in emotional and cognitive processing have been reported during premenstrual phase in women of reproductive age.
Vaishali M Paunikar, D Rajashree
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Effect of chewing tobacco on reaction time – A comparative study

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology
Background: The smoked and smokeless forms of tobacco consist of about 4000 chemical constituents having carcinogenic potential and nicotine is the major among these.
Varsha M Shindhe   +5 more
doaj   +1 more source

Effect of helmet use on visual and auditory reaction time and peripheral field of vision

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2019
Background: In many Asian countries, motorcycles are an important means of transportation. The effectivity of helmets in reducing head injuries is studied, but the effect of helmets on the auditory and visual reaction time and peripheral field of vision ...
Prema Krishnarao Joshi   +2 more
doaj   +1 more source

Two separate, large cohorts reveal potential modifiers of age-associated variation in visual reaction time performance. [PDF]

open access: yesNPJ Aging Mech Dis, 2021
Talboom JS   +17 more
europepmc   +1 more source

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