Results 91 to 100 of about 4,996,743 (329)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Learning a Recurrent Visual Representation for Image Caption Generation
, 2014 In this paper we explore the bi-directional mapping between images and their sentence-based descriptions. We propose learning this mapping using a recurrent neural network.
Chen, Xinlei, Zitnick, C. Lawrence
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Études Britanniques Contemporaines, 2013 Martin Amis’s choice of topic for Time’s Arrow seems to confirm his reputation as a controversial figure and to turn the novel into material for explosive debate.
Diane Leblond
doaj +1 more source
Representation of Samba dance gestures, using a multi-modal analysis approach [PDF]
, 2008 In this paper we propose an approach for the representation of dance gestures in Samba dance. This representation is based on a video analysis of body movements, carried out from the viewpoint of the musical meter.
Leman, Marc, Naveda, Luiz Alberto
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Learning weakly supervised multimodal phoneme embeddings
, 2017 Recent works have explored deep architectures for learning multimodal speech representation (e.g. audio and images, articulation and audio) in a supervised way. Here we investigate the role of combining different speech modalities, i.e.
Chaabouni, Rahma +3 more
core +3 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Schematic Visual Representation of Exponentiation [PDF]
Revija za Elementarno Izobraževanje, 2015 Visualization of mathematical concepts is an effective learning and teaching strategy. Within mathematics lessons, visualisation is mostly present at iconic level, where concepts are graphically represented.
Darja Antolin, Urška Lipovec
doaj