Results 51 to 60 of about 470,081 (296)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Evaluation of visual stress symptoms in age-matched dyslexic, Meares-Irlen syndrome and normal adults. [PDF]

open access: yesInt J Ophthalmol, 2016
AIM: To examine the prevalence of dyslexia and Meares-Irlen syndrome (MIS) among female students and determine their level of visual stress in comparison with normal subjects.
Alanazi MA, Alanazi SA, Osuagwu UL.
europepmc   +2 more sources

Effects of Thermal Stress on Dual Task Performance and Attention Allocation

open access: yes, 2005
A visual-visual dual task was designed to test the effect of the thermal environment on dual task performance and attention allocation. The temperatures selected for testing were 20 and 35°C Wet Bulb Globe Temperature (WBGT) in experiment 1 and 25, 30 ...
Waldemar Karwowski   +7 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Visual aspects in urban woodland management and planning [PDF]

open access: yes, 2003
Urban woodland is an important component of people's everyday environment, both as an attractive environment to visit as well as being an intrinsic part of the surrounding landscape.
Ode, Åsa
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Posttraumatic stress, visual working memory, and visual imagery in military personnel

open access: yesCurrent Psychology, 2023
AbstractPosttraumatic stress disorder (PTSD) is characterized by disruptions to cognitive functioning. Two studies were conducted to examine the relevance of military-related PTSD to two cognitive functions – visual working memory and visual imagery.
Brenton Russell, Alexander J. Mussap
openaire   +2 more sources

Sildenafil-evoked photoreceptor oxidative stress in vivo is unrelated to impaired visual performance in mice.

open access: yesPLoS ONE, 2021
PurposeThe phosphodiesterase inhibitor sildenafil is a promising treatment for neurodegenerative disease, but it can cause oxidative stress in photoreceptors ex vivo and degrade visual performance in humans.
Bruce A Berkowitz   +16 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Activity-dependent plasticity in visual forebrain areas of the zebra finch

open access: yes, 1996
Rollenhagen A, Bischof H-J. Activity-dependent plasticity in visual forebrain areas of the zebra finch. Behavioural Brain Research.
Rollenhagen, Astrid   +3 more
core   +1 more source

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