Results 101 to 110 of about 1,205,804 (266)

EXPOSURE OF HUMAN RPE CELLS TO SERUM FROM AMD PATIENTS MIMICS THE EARLY STAGES OF THE DISEASE IN VITRO.

IBRO Neuroscience Reports, 2023
Lucía San José Lassalle, Alicia Segurado, Iván Aldavero Muñoz, Almudena Velasco Arranz, Concepción Lillo Delgado   +4 more
doaj   +1 more source

Early life maturation of human visual system white matter is altered by monocular enucleation [PDF]

, 2019
Benjamin T. Dunkley, Marlee M. Vandewouw, Arijit Chakraborty, Margot J. Taylor, Brenda L. Gallie, Daphne L. McCulloch, Benjamin Thompson   +6 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Building Goal-Oriented Dialogue Systems with Situated Visual Context [PDF]

, 2022
Sanchit Agarwal, Jan Jeżabek, Arijit Biswas, Emre Barut, Shuyang Gao, Tagyoung Chung   +5 more
openalex   +1 more source

Card games are effective tools to enhance foundation year health and safety inductions

FEBS Open Bio, EarlyView.
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq, Holly Matthews, Daniya Abedalreza, Faten Yahya, Matthew Allan Jones   +4 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Multiple objects evoke fluctuating responses in several regions of the visual pathway

eLife
How neural representations preserve information about multiple stimuli is mysterious. Because tuning of individual neurons is coarse (e.g., visual receptive field diameters can exceed perceptual resolution), the populations of neurons potentially ...
Meredith N Schmehl, Valeria C Caruso, Yunran Chen, Na Young Jun, Shawn M Willett, Jeff T Mohl, Douglas A Ruff, Marlene Cohen, Akinori F Ebihara, Winrich A Freiwald, Surya T Tokdar, Jennifer M Groh   +11 more
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Visual system involvement in patients with Friedreich's ataxia [PDF]

, 2008
F. Fortuna, Piero Barboni, Rocco Liguori, Maria Lucia Valentino, Giacomo Savini, Cinzia Gellera, Caterina Mariotti, Giovanni Rizzo, Caterina Tonon, David Neil Manners, Raffaele Lodi, Alfredo A. Sadun, Valério Carelli   +12 more
openalex   +1 more source