Results 41 to 50 of about 1,224,970 (257)

A theoretical model reveals specialized synaptic depressions and temporal frequency tuning in retinal parallel channels

open access: yesFrontiers in Computational Neuroscience, 2022
In the Outer Plexiform Layer of a retina, a cone pedicle provides synaptic inputs for multiple cone bipolar cell (CBC) subtypes so that each subtype formats a parallelized processing channel to filter visual features from the environment.
Liuyuan He   +7 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Human Color Perception: The Impact of Color Perception on Fine-Grained Emotion Prediction in Movie and Television Videos

open access: yesSensors
This article investigates the impact of visual color perception on fine-grained emotion prediction in videos, analyzing the contribution of color perception features in fine-grained emotion prediction.
Shuang Wang   +6 more
doaj   +1 more source

Opsin genes: research perspectives with Neotropical cichlids (Perciformes: Cichlidae) and their relevance in floodplain studies

open access: yesActa Scientiarum: Biological Sciences, 2016
Vision not only plays an important role in the behavior and exploration capacity of new ecology niches but also influences the evolution of species exposed to the heterogeneity of light.
Thomaz Mansini Carrenho Fabrin   +3 more
doaj   +1 more source

Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson’s Disease

open access: yesFrontiers in Neuroscience, 2021
Despite decades of research, disease-modifying treatments of Parkinson’s disease (PD), the second most common neurodegenerative disease worldwide, remain out of reach.
Lien Veys   +11 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Lens Thickness in Infants and Children with Cataracts

open access: yesOphthalmology Science
Purpose: The purpose of this study was to determine the association between lens thickness and cataract in participants aged 0 to 5 years. Design: This was a prospective, multicenter, case–control study.
Libby Wei, MD   +13 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Automated strabismus evaluation: a critical review and meta-analysis

open access: yesFrontiers in Neurology
IntroductionAdult strabismus has a wide range of etiologies and necessitates clinical evaluation for appropriate treatment. Advancements in eye tracking technology show promise for the development of clinically accurate, automated evaluation and ...
Emma M. Hartness   +13 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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