Results 81 to 90 of about 7,551,855 (242)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Jurnal Sains Sosial dan Humaniora, 2019 Tujuan penelitian ini adalah untuk mengembangkan keterampilan sosial peserta didik yang mengalami gangguan kecemasan sosial dengan menggunakan model pembelajaran strategi berpikir visual di sekolah dasar. Penelitian ini menggunakan pendekatan kuantitatif,
S Sriyanto +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Towards an Integrated Educational Practice: Application of Systems Thinking in STEM Disciplines
SystemsSystems thinking is not a static concept, but rather a dynamic and evolving paradigm that continually adapts to the challenges of its time, becoming more refined and applicable in different areas, such as education.
Selene Castañeda-Burciaga +10 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Pedagogic strategies to support learning design thinking in a masters course [PDF]
, 2013 The demand for further skills and qualifications in the educational technology field remains strong as the range of technologies increases and their potential use in educational contexts becomes more compelling. Students registering for the University of
Hodgkinson-Williams, Cheryl +1 more
core +1 more source
The Effect of Visual Thinking Strategies on Iraqi EFL Students` Communication Skills
مجلة كلية التربية للبناتThe goal of the study is to find out the effect of the visual thinking strategies (VTS) upon the college students` achievement in English language communication skills. To achieve the aim of the study, the experimental posttest design is used.
Elaf Riyadh Khalil
doaj +1 more source
DEPENDENCE OF CONCEPTUAL THINKING ON QUALITATIVE CHARACTERISTICS OF ITS ACTIVITY
Вестник Кемеровского государственного университета, 2018 The article features the results of the research that considers qualitative characteristics of thinking as a cognitive mental process. The research group included young people and adolescents.
E. V. Valiullina
doaj +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source