Results 91 to 100 of about 7,607,853 (297)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Semantic knowledge influences visual working memory in adults and children.

open access: yesPLoS ONE, 2020
We can retain only a portion of the visual information that we encounter within our visual working memory. Which factors influence how much information we can remember?
Ariel Starr   +2 more
doaj   +1 more source

Working Memory in the Primary Visual Cortex [PDF]

open access: yesArchives of Neurology, 2003
The primary visual cortex is the first cortical area of the visual system that receives information from the external visual world. Neurons in the primary visual cortex have small receptive fields and respond to basic elements of the visual scene. Recent findings, however, show that the primary visual cortex is also involved in cognitive processes ...
openaire   +2 more sources

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Spatial working memory in visual search for multiple targets

open access: yesЭкспериментальная психология, 2017
The article investigated the role of spatial working memory in visual search for multiple targets, in particular, in subsequent search misses effect. This phenomenon is the second target omission after the first target has been found in visual
E.S. Gorbunova
doaj   +1 more source

The contributions of visual and central attention to visual working memory [PDF]

open access: yesAttention, Perception, & Psychophysics, 2017
We investigated the role of two kinds of attention-visual and central attention-for the maintenance of visual representations in working memory (WM). In Experiment 1 we directed attention to individual items in WM by presenting cues during the retention interval of a continuous delayed-estimation task, and instructing participants to think of the cued ...
Souza, Alessandra S, Oberauer, Klaus
openaire   +3 more sources

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky   +5 more
wiley   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

The attentional blink reveals serial working memory encoding: Evidence from virtual and human event-related potentials [PDF]

open access: yes, 2009
Observers often miss a second target (T2) if it follows an identified first target item (T1) within half a second in rapid serial visual presentation (RSVP), a finding termed the attentional blink.
Craston, Patrick   +4 more
core   +1 more source

Analysis of influencing factors of visual working memory in young adult patients with schizophrenia

open access: yesGeneral Psychiatry, 2018
Background Patients with schizophrenia have general cognitive impairments, and the impairment of working memory is considered to be the basis of cognitive impairments.
Li Liu   +6 more
doaj   +1 more source

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