Results 71 to 80 of about 63,753 (287)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Detailed sensory memory, sloppy working memory

open access: yesFrontiers in Psychology, 2010
Visual short-term memory (VSTM) enables us to actively maintain information in mind for a brief period of time after stimulus disappearance. According to recent studies, VSTM consists of three stages - iconic memory, fragile VSTM, and visual working ...
Ilja G Sligte   +3 more
doaj   +1 more source

Modulation of Visual Working Memory Performance via Different Theta Frequency Stimulations

open access: yesBrain Sciences, 2021
Previous studies have found that transcranial alternating current stimulation (tACS) can significantly enhance individuals’ working memory performance. However, it is still unclear whether the memory performance enhancement was attributed to the quantity
Xue Guo   +3 more
doaj   +1 more source

Additive Manufacturing of Continuous Fibre Reinforced Composites: Process, Characterisation, Modelling, and Sustainability

open access: yesAdvanced Engineering Materials, EarlyView.
Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley   +1 more source

Angry expressions strengthen the encoding and maintenance of face identity representations in visual working memory [PDF]

open access: yes, 2014
This work was funded by a BBSRC grant (BB/G021538/2) to all authors.Peer ...
Jackson, Margaret C.   +5 more
core   +1 more source

Multimodal Data‐Driven Microstructure Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang   +4 more
wiley   +1 more source

Does spatial attention modulate sensory memory?

open access: yesPLoS ONE, 2019
According to some theoretical models, information contained in visual short-term memory (VSTM) consists of two main memory stages/storages: sensory memory, a system wherein information is stored for a brief time with high detail and low resistance to ...
Fabiano Botta   +3 more
doaj   +1 more source

Proactive interference does not meaningfully distort visual working memory capacity estimates in the canonical change detection task

open access: yesFrontiers in Psychology, 2012
The change detection task has become a standard method for estimating the storage capacity of visual working memory. Most researchers assume that this task isolates the properties of an active short-term storage system that can be dissociated from long ...
Po-Han eLin, Steven J Luck
doaj   +1 more source

A probabilistic palimpsest model of visual short-term memory.

open access: yes, 2015
Working memory plays a key role in cognition, and yet its mechanisms remain much debated. Human performance on memory tasks is severely limited; however, the two major classes of theory explaining the limits leave open questions about key issues such as ...
Dayan, P.   +11 more
core   +1 more source

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

open access: yesAdvanced Engineering Materials, EarlyView.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele   +2 more
wiley   +1 more source

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