Results 71 to 80 of about 47,226 (310)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

La topología aplicada al lenguaje visual

Kepes, 2008
La topología, como elemento inherente a las ciencias y a las matemáticas, puede ser llevada al territorio del arte. En las alternativas plásticas modernas y contemporáneas, es factible rastrear la influencia de la topografía tanto en la designación del ...
Graciela . Marotta
doaj  

La potencia edu(vo)cautiva de los artefactos visuales.

Arte e Investigación, 2019
Este artículo tiene como objetivo delinear estrategias educativas en torno a las imágenes, bajo la perspectiva de la cultura visual. Utilizaré la hibridación de los términos educativo, evocativo, cautivo —edu(vo)cautiva— para abordar las experiencias de ...
Lutiere Dalla Valle
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

La investigación extradisciplinar en artes visuales: prácticas colaborativas y aprendizajes comunes. (Hacia una nueva relación en las ciencias sociales. La comunicación, el arte y la educación en cuestión) [PDF]

, 2015
[EN] This essay raises certain problems that claim artistic production, not as objects of knowledge, but as a form of knowledge itself. The issues raised are to build a territory about the "what" and " how " to relocate to possible territory of artistic ...
Villaplana Ruiz, Virginia
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Los Estudios Visuales. Un estado de la cuestión

, 2003
El discurso de la apropiación, las teorías posestructuralistas de la muerte del autor y de la deconstrucción, el cuestionamiento de la representación y el discurso de la diferencia fueron decisivos para cuestionar algunos de los valores asociados a la ...
Guasch, Ana María
core  

Using Visualization to Debug Visualization Software [PDF]

IEEE Computer Graphics and Applications, 2010
This article provides useful strategies for debugging visualization software.The key to debugging visualization software is to exploit the strengths of computer graphics and visualization.
openaire   +3 more sources