Results 221 to 230 of about 3,298,081 (299)

Visualization of the True Left Ventricular Apex on Transthoracic Echocardiography. [PDF]

Echocardiography
Okazaki N, Baba Y, Ochi Y, Kawaguchi J, Hirakawa D, Kubo T, Yamasaki N, Tokuhiro S, Kitaoka H.   +8 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Tubular spinal micro decompression surgery with integrated 2D camera visualization: initial experience and feasibility in Tanzania. [PDF]

Acta Neurochir (Wien)
Bureta C, Sabas RR, Cadieux M, Garvayo M, Sisay BG, Bui T, Ikwuegbuenyi CA, Shabani HK, Härtl R.   +8 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimizing Territorial Healthcare Networks with a Capacity-Constrained Hub-And-Spoke Allocation Algorithm: The Province of L'Aquila Case Study. [PDF]

Healthcare (Basel)
Trebbi E, Barlattani T, Bologna A, Tognaccini L, Sili A, Di Martino G, Stan C, Odio C, Staniscia T, Pacitti F, Romano F.   +10 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Definitive Airway Management in Sepsis-Related Airway Edema Following a Failed Intubation: An Anesthesia-Guided Approach to High-Risk Airway Management. [PDF]

Cureus
Jafri M, Khan Z, Payappagoudar G, Jafri H, Lambroussis CG.   +4 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Comparative analysis of robotic vs. laparoscopic right hepatectomy: propensity score matching and machine learning analysis for outcome prediction. [PDF]

Front Surg
Mazzotta AD, Samer D, Salina G, Ratti F, Baldisseri F, Magistri P, Belli A, Ceccarelli G, Izzo F, Spampinato MG, De' Angelis N, Pessaux P, Piardi T, Di Benedetto F, Ammendola M, Aldrighetti L, Mennini G, Tedeschi M, Memeo R, Soubrane O.   +19 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source