Results 311 to 320 of about 4,045,707 (379)

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Innovative Integration of 4D Cardiovascular Reconstruction and Hologram: Framework Development of a New Visualization Tool for Coronary Artery Bypass Grafting Planning.

JMIR Med Inform
Wang S, Ren T, Cheng N, Zhang L, Wang R.
europepmc   +1 more source

Heart 3D: echocardiographic and anatomical features of the tricuspid valve in a heterogeneous population with severe regurgitation-implications for edge-to-edge procedure suitability. [PDF]

Front Cardiovasc Med
Sobieraj J, Rdzanek A, Kapłon-Cieślicka A, Huczek Z, Tomaniak M, Ostrowska E, Piasecki A, Pędzich E, Scisło P.   +8 more
europepmc   +1 more source

Visualization of central noradrenergic neurons in thick sections by the unlabeled antibody method: a transmitter-specific Golgi image.

, 1978
Reinhard Grzanna, M.E. Molliver, Joseph T. Coyle   +2 more
openalex   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Visualization of Medical Record with 3D Human Body Models. [PDF]

Healthcare (Basel)
Liu TJ, Lai CY, Chiang YC.
europepmc   +1 more source

Electron microscopic visualization of tRNA genes with ferritin-avidin: biotin labels

, 1978
Thomas R. Broker, Lynne M. Angerer, Pauline H. Yen, Neil D. Hershey, Norman Davidson   +4 more
openalex   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Research on Multi-Sensor Data Fusion Based Real-Scene 3D Reconstruction and Digital Twin Visualization Methodology for Coal Mine Tunnels. [PDF]

Sensors (Basel)
Zhu H, Jin J, Zhao S.
europepmc   +1 more source