Results 131 to 140 of about 5,335,329 (375)

The State of General Operating Support 2011 [PDF]

, 2012
In 2011, 1,121 American grantmakers reported $5.9 billion in general operating support, a substantial increase (83 percent) over average core support from 2008-2010.
Kevin Laskowski, Niki Jagpal
core   +1 more source

Systemic Innate Immune System Restoration as a Therapeutic Approach for Neurodegenerative Disease: Effects of NP001 on Amyotrophic Lateral Sclerosis (ALS) Progression

Biomedicines
Background/objective: Amyotrophic lateral sclerosis (ALS) is a diagnosis that incorporates a heterogeneous set of neurodegenerative processes into a single progressive and uniformly fatal disease making the development of a uniformly applicable ...
Michael S. McGrath, Rongzhen Zhang, Paige M. Bracci, Ari Azhir, Bruce D. Forrest   +4 more
doaj   +1 more source

Changes in forced vital capacity over time in systemic sclerosis: application of group-based trajectory modelling.

Rheumatology, 2015
OBJECTIVE An accelerated rate of decline in forced vital capacity (FVC) affects >50% of patients with SSc but data on the variability and determinants of this change are scarce.
Ada Man, T. Davidyock, Laura T Ferguson, M. Ieong, Yuqing Zhang, R. Simms   +5 more
semanticscholar   +1 more source

Moderators and mediators of pain and function outcomes in a new service delivery model for management of knee osteoarthritis in primary care (PARTNER): Secondary exploratory analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective Explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (PARTNER), at 12 months (ACTRN12617001595303). Methods Secondary analyses of a cluster randomized controlled trial comparing PARTNER to usual general practitioner‐delivered ...
Abdolhay Farivar, Jocelyn L Bowden, Kim L Bennell, Andrew M Briggs, Stephen J Bunker, Rana S Hinman, Thorlene Egerton, Simon D French, Marie Pirotta, Karen Schuck, Venkatesha Venkatesha, Nicholas A Zwar, David J Hunter   +12 more
wiley   +1 more source

Comparison between the effects of high sevoflurane concentration during induction of anasesthesia using vital capacity breath and tidal breathing techniques in adults [PDF]

, 2009
Introduction: The aims of this randomised study were to compare the induction characteristics of sevoflurane using vital capacity breath technique to that of tidal breathing technique in adults undergoing day-care surgery, and to compare patients ...
Ibrahim, Noor Airini, Lim, K. Y., P. Shanmugam, Suresh Kumar, Wong, Wai Hong   +3 more
core  

Lung development genes, adult lung function and cognitive traits [PDF]

Lower lung function is associated with lower cognitive function and an increased risk of dementia. This has not been adequately explained and may partly reflect shared developmental pathways. In UK Biobank participants of European ancestry, we tested the
Dodd, James W, Jacobs, Benjamin M, Marshall, Charles R, Minelli, Cosetta, Portas, Laura, Shaheen, Seif O, Talaei, Mohammad, Waters, Sheena   +7 more
core   +3 more sources

Threats, Protection and Attribution of Cyber Attacks on Critical Infrastructures [PDF]

arXiv, 2019
As Critical National Infrastructures are becoming more vulnerable to cyber attacks, their protection becomes a significant issue for any organization as well as a nation. Moreover, the ability to attribute is a vital element of avoiding impunity in cyberspace.
arxiv  

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Treinamento aeróbico melhora a capacidade funcional de pacientes em hemodiálise crônica Aerobic exercise improves physical capacity in patients under chronic hemodialysis

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: Na população geral, a prática regular de exercícios físicos se associa à melhora da capacidade funcional e à redução de eventos cardiovasculares.
Diane Michela Nery Henrique, Maycon de Moura Reboredo, Alfredo Chaoubah, Rogério Baumgratz de Paula   +3 more
doaj  

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source