Results 21 to 30 of about 3,971,224 (257)

Impairment in Respiratory Function Contributes to Olfactory Impairment in Amyotrophic Lateral Sclerosis

open access: yesFrontiers in Neurology, 2018
BackgroundNonmotor symptoms are very common in neurodegenerative diseases. In patients suffering from amyotrophic lateral sclerosis (ALS), olfactory dysfunction was first reported more than 20 years ago; however, its pathophysiological correlates and ...
René Günther   +10 more
doaj   +1 more source

Impact of Short-Term Bhastrika Pranayama on Respiratory Parameters: An Ancient Practice with Contemporary Significance

open access: yesPhysical Education of Students, 2015
Purpose: The study was conducted to determine the impact of short-term bhastrika pranayama on respiratory parameters. Material : The research was carried out on a sample of 30 university level girls. Experimental group was subjected to 4-week training of
Singh Bal Baljinder
doaj   +1 more source

A study of different predictors of successful weaning off mechanical ventilation in ventilated patients with chronic obstructive pulmonary disease with acute respiratory failure

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2020
Background A lot of indices can be used as predictors of weaning off mechanical ventilation, such as rapid shallow breathing index (RSBI), integrative weaning index (IWI), vital capacity (VC), maximal inspiratory pressure (MIP), and respiratory rate (RR).
Asmaa A El-Daim   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

PERBANDINGAN PARAMETER FUNGSI PARU ATLET PUTRA CABANG OLAHRAGA BOLA VOLI DENGAN SEPAK TAKRAW DI PUSAT PENDIDIKAN DAN LATIHAN PELAJAR JAWA TENGAH

open access: yesJurnal Kedokteran Diponegoro, 2016
Latar belakang : Beberapa cabang olahraga prestasi yang dilatih secara intensif di PPLP untuk ditingkatkan prestasinya diantaranya adalah cabang olahraga Bola Voli dan Sepak Takraw.
Aulia Izzati   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Brazilian consensus on Duchenne muscular dystrophy. Part 2: rehabilitation and systemic care

open access: yesArquivos de Neuro-Psiquiatria
Significant advances in the understanding and management of Duchenne muscular dystrophy (DMD) have occurred since the publication of international guidelines for DMD care in 2010.
Alexandra P. Q. C. Araujo   +10 more
doaj   +1 more source

Smoking exposure, loss of forced expiratory volume in one second and the risk of lung cancer among patients with malignant disease who present with cardiac or pulmonary symptoms: a cross-sectional study

open access: yesTobacco Induced Diseases, 2017
Introduction Smokers with airway obstruction are at a higher risk of lung cancer than smokers without airway obstruction. Inflammation plays a key role in lung carcinogenesis.
Siegfried Wieshammer, Jens Dreyhaupt
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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