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BackgroundNonmotor symptoms are very common in neurodegenerative diseases. In patients suffering from amyotrophic lateral sclerosis (ALS), olfactory dysfunction was first reported more than 20 years ago; however, its pathophysiological correlates and ...
René Günther +10 more
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Purpose: The study was conducted to determine the impact of short-term bhastrika pranayama on respiratory parameters. Material : The research was carried out on a sample of 30 university level girls. Experimental group was subjected to 4-week training of
Singh Bal Baljinder
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Background A lot of indices can be used as predictors of weaning off mechanical ventilation, such as rapid shallow breathing index (RSBI), integrative weaning index (IWI), vital capacity (VC), maximal inspiratory pressure (MIP), and respiratory rate (RR).
Asmaa A El-Daim +3 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Latar belakang : Beberapa cabang olahraga prestasi yang dilatih secara intensif di PPLP untuk ditingkatkan prestasinya diantaranya adalah cabang olahraga Bola Voli dan Sepak Takraw.
Aulia Izzati +2 more
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Brazilian consensus on Duchenne muscular dystrophy. Part 2: rehabilitation and systemic care
Significant advances in the understanding and management of Duchenne muscular dystrophy (DMD) have occurred since the publication of international guidelines for DMD care in 2010.
Alexandra P. Q. C. Araujo +10 more
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Introduction Smokers with airway obstruction are at a higher risk of lung cancer than smokers without airway obstruction. Inflammation plays a key role in lung carcinogenesis.
Siegfried Wieshammer, Jens Dreyhaupt
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
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