Results 121 to 130 of about 1,324,081 (316)

Predictors of readmission and health related quality of life in patients with chronic heart failure: a comparison of different psychosocial aspects [PDF]

, 2018
Psychological distress is common in patients with chronic heart failure. The impact of different psychological variables on prognosis has been shown but the comparative effects of these variables remain unclear.
Barth, Jürgen, Kohls, Sonja, Saner, Hugo, Schmid, Jean-Paul, Volz, Andreas, Zwahlen, Marcel   +5 more
core  

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang, Ming‐Ju Amy Lyu, Ze Hong, Jing Sun, Lan Guo, Jiameng Hu, Munire Maimaiti, Chenhui Li, Jinyi Song, Xiang Zhang, Huansha Yu, Chen Wang, Xuan Wang, Haiyang Hu   +13 more
wiley   +1 more source

Sex differences in the combined effect of chronic stress with impaired vascular endothelium functioning and the development of early atherosclerosis: The Cardiovascular Risk in Young Finns study

BMC Cardiovascular Disorders, 2010
Background The syndrome of vital exhaustion (VE), characterized by fatigue and irritability, may contribute to an increased risk of atherosclerosis.
Juonala Markus, Hintsanen Mirka, Chumaeva Nadja, Raitakari Olli T, Keltikangas-Järvinen Liisa   +4 more
doaj   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

Advanced Science, EarlyView.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner, Truls Raastad, Max Ullrich, Stian F. Christiansen, Hazel Sutherland, James Boot, Eva Wozniak, Charles Mein, Emilie Dalbram, Jonas T. Treebak, Daniel J. Owens, David C. Hughes, Sue C. Bodine, Jonathan C. Jarvis, Adam P. Sharples   +14 more
wiley   +1 more source

Assessment of Burnout in the General Population of France: Comparing the Maslach Burnout Inventory and the Copenhagen Burnout Inventory

Mental Health Science
Burnout is an occupational phenomenon that arises from the unsuccessful management of chronic job stress. Accurate measures of burnout are vital for the implementation of effective interventions.
Lucia Romo, Oulmann Zerhouni, Stéphanie Nann, Erwan Rebuffe, Samantha Tessier, Chloé Touzé, Laurent Cruchet, Clément Duret   +7 more
doaj   +1 more source

Workplace bullying and employees’ turnover intention in hospitality industry: evidence of Nepal

Cogent Business & Management
Bullying influence individuals, organizations and society, requiring support for individuals, causing mental stress leading to exhaustion and potential employee turnover.
Gangaram Biswakarma, Perdoor Sreeramana Aithal, Sanju Kumar Singh, Achyut Gnawali, Jayanta Ghimire   +4 more
doaj   +1 more source

Stress, crisis and trauma as indivisible part of life: Basic theory of survival psychology [PDF]

Zbornik Radova Filozofskog Fakulteta u Prištini, 2009
Stress affects the mental health in many ways. Scientists are not compatible what mental health represents, not even in terminology and definitions of stress, crisis and trauma.
Jeknić Petar
doaj  

07 Intern Assignment Biological Adaptations [PDF]

, 2020
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source