Results 21 to 30 of about 167,425 (277)

Analysis of the vital exhaustion construct in a female population during cardiac rehabilitation

Monaldi Archives for Chest Disease, 2015
Background: Vital Exhaustion (VE) is a psychological construct that has been shown to be predictive for cardiac morbidity and mortality. There are not sufficient data which clarify whether the female population express this construct differentely ...
Gianluigi Balestroni, Pantaleo Giannuzzi, Giovanna Omarini, Pierangela Omarini   +3 more
doaj   +1 more source

Association of the dopamine receptor (DRD4, DAT) gene polymorphisms with vital exhaustion in an open population among 25—64-year-old men (Novosibirsk): Epidemiological study according to the WHO MONICA-psychosocial program

Неврология, нейропсихиатрия, психосоматика, 2012
Objective: to study the association of the DRD4, DAT genes with vital exhaustion in an open 25—64-old-year male population. A random representative sample of 657 men aged 25—64 years, living in one of the Novosibirsk districts was examined within the WHO
Valery Vasilyevich Gafarov, M I Voyevoda, E A Gromova, V N Maksimov, A V Gafarova, I V Gagulin, N S Yudin, T M Mishakova   +7 more
doaj   +1 more source

Vital exhaustion and risk development of the stroke in general population men in 25–64 years old (epidemiological investigation of basis program WHO MONICA-psychosocial)

Бюллетень сибирской медицины, 2009
Risk of the stroke in population men in 25–64 years old with vital exhaustion in the course of 14 years was examined. WHO-MONICA-psychosocial program are using. Workers and low education men has risk of the stroke more often. Risk of the stroke in the 25–
V. V. Gafarov, Ye. A. Gromova, A. V. Gafarova, Yu. N. Kabanov, I. V. Gagulin   +4 more
doaj   +1 more source

Mechanisms of CAR T cell exhaustion and current counteraction strategies

Frontiers in Cell and Developmental Biology, 2022
The functional state of chimeric antigen receptor T (CAR T) cells determines their efficacy in vivo. Exhausted CAR T cells exhibit decreased proliferative capacity, impaired anti-tumor activity, and attenuated persistence.
Xiaoying Zhu, Qing Li, Xiaojian Zhu
doaj   +1 more source

Stress reactivity, cognitive functioning and hippocampal morphology in exhaustion disorder, and development of a self rating scale for exhaustion disorder, KEDS [PDF]

, 2012
Stress is considered a major health problem in modern society and a prominent reason behind the long term sick leave (LTSL). Chronic stress may give rise to feelings of irritation and fatigue or exhaustion and may precipitate depression and anxiety as ...
Wahlberg, Kristina
core   +1 more source

Vital Exhaustion and Somatic Depression [PDF]

Psychosomatic Medicine, 2012
To test whether vital exhaustion overlaps more with somatic/affective depression than with cognitive/affective depressive symptoms and evaluate the risk of recurrent cardiovascular events associated with these constructs.The Beck Depression Inventory (BDI) and the Maastricht Questionnaire (MQ) were administered to 528 patients hospitalized with ...
Vroege, Esther M., Zuidersma, Marij, de Jonge, Peter   +2 more
openaire   +2 more sources

Receptor signaling, transcriptional, and metabolic regulation of T cell exhaustion

OncoImmunology, 2020
Exhaustion cripples T cell effector responses against metastatic cancers and chronic infections alike. There has been considerable interest in understanding the molecular and cellular mechanisms driving T cell exhaustion in human cancers fueled by the ...
Mumtaz Y. Balkhi
doaj   +1 more source

Vital exhaustion and risk of alcohol use disorders: A prospective cohort study [PDF]

Journal of Psychosomatic Research, 2018
Vital exhaustion is an emotional state characterized by fatigue and depressive symptoms. We examined the prospective association between vital exhaustion and risk of alcohol use disorders (AUD). Furthermore, we investigated whether cohabitation status modifies the effect of this potential association.Vital exhaustion was assessed by a condensed, 17 ...
Just-Østergaard, Emilie, Mortensen, Erik L, Tolstrup, Janne S., Flensborg-Madsen, Trine   +3 more
openaire   +3 more sources

COMT Val158Met (rs4680) polymorphism and vital exhaustion in an open 45–64-year-old population (international epidemiological WHO MONICA and HAPIEE programs)

Неврология, нейропсихиатрия, психосоматика, 2019
Objective: to study the association of the polymorphic genotypes of rs4680 in the catechol-O-methyl transferase (COMT) gene with vital exhaustion (VE) in a 45–64-year-old population. Patients and methods.
V. V. Gafarov, E. A. Gromova, D. O. Panov, V. N. Maksimov, I. V. Gagulin, E. A. Krymov, A. V. Gafarova   +6 more
doaj   +1 more source

Epidemiological study of vital exhaustion and sleep disorders in dwellers of Siberia

Неврология, нейропсихиатрия, психосоматика, 2016
Objective: to study the prevalence of vital exhaustion (VI) and sleep disorders, the pattern of the latter in 45–69-year-old Novosibirsk dwellers (Siberia) with different levels of VI.Patients and methods. A random representative sample of 45–69-year-old
I. V. Gagulin, V. V. Gafarov, E. A. Gromov, A. V. Gafarova, D. O. Panov   +4 more
doaj   +1 more source