Results 81 to 90 of about 1,324,081 (316)

Beta-blockers and physical frailty in patients with end-stage liver disease. [PDF]

, 2018
AimTo investigate beta-blocker (BB) use in patients with cirrhosis and determine their effects on physical frailty and overall survival.MethodsAdult outpatients with cirrhosis listed for liver transplantation underwent testing of physical frailty using ...
Hayssen, Hilary, Kuo, Selena Z, Lai, Jennifer C, Lizaola, Blanca   +3 more
core  

Single‐Cell RNA Sequencing of Human Lung Tissues Reveals Metallothionein‐Positive T Cells as a Novel Potential Marker of Susceptibility to Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing of lung samples and flow cytometry of peripheral blood, we identified a novel T cell subset with high metallothionein (MT) expression. These MT‐high T cells suppress CD8+ T cell cytotoxicity and are progressively depleted from healthy controls to chronic obstructive pulmonary disease (COPD) patients, positioning them as
Zengqing Liu, Xiaoxia Ren, Mi Mu, Huanyu Long, Jialu Lv, Zhihong Feng, Jie Liu, Jiajia Wang, Hui Deng, Fanyu Shi, Muzhi Zhang, Ruoyang Zhang, Yang Liu, Mengyu Xu, Yang Fan, Zengtao Wang, Zhe Lv, Yan Chen, Chris J. Corrigan, Ying Sun, Yahong Chen, Chen Chen, Ye Cui, Wei Wang   +23 more
wiley   +1 more source

Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers [PDF]

, 2017
There is a complex bidirectional relationship between stress and epilepsy. Stressful stimuli and subsequent cortisol release act as a trigger for seizure activity in some individuals with epilepsy, and seizure activity itself may act as a stressor to the
Fowkes, R C, Packer, R M A, Volk, H A
core   +1 more source

Increased vital exhaustion among type-D patients with ischemic heart disease [PDF]

Journal of Psychosomatic Research, 2001
To investigate the prevalence of the "distressed personality" (type-D) in cardiac patients and to explore the relationships between type-D, gender, vital exhaustion and angina pectoris.A questionnaire was completed by 171 patients scheduled for coronary angiography (CAG) at baseline and again at 6 weeks following implementation of treatment with ...
Pedersen, SS, Middel, B
openaire   +4 more sources

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Engagement of employees in a research organisation: A relational perspective

South African Journal of Economic and Management Sciences, 2017
Background: Increasing work engagement in a sustainable way remains a challenge despite years of research on the topic. Relationships at work are vital to foster engagement or disengagement.
Doris Asiwe, Sebastiaan Rothmann, Lene Jorgensen, Carin Hill   +3 more
doaj   +1 more source

Iowa Health Focus, August 2006 [PDF]

, 2006
Monthly newsletter for the Iowa Department of Public ...

core  

Disulfide‐Bridged Ru Complex–Mediated Photo‐Disulfidptosis for Colorectal Cancer Therapy

Advanced Science, EarlyView.
In this work, a binuclear ruthenium complex, RuSSRu was developed for efficient colorectal cancer (CRC) treatment. The synergistic interaction between disulfidptosis and lysosomal damage‐induced apoptosis induced by RuSSRu amplified tumor cell death. This innovative approach offers a potent therapeutic strategy for CRC.
Simeng He, Wendong Jin, Jiaojiao Pang, Xiaoting Gong, Shixian Cao, Duo Mao, Yuguo Chen, Kang‐Nan Wang, Bin Liu   +8 more
wiley   +1 more source

Vital Exhaustion in hypothyroid patients before and after levothyroxine treatment1

Revista de Psicología, 2019
The objective of this paper was to prove the existence of Vital Exhaustion (VE) in patients with Primary Hypothyroidism (PH), if PH treatment modifies VE, and if there is an association between TSH and VE response to treatment.
Inés Manzano, José Bonet
doaj  

Psychosocial work environment and emotional exhaustion among middle-aged employees

BMC Research Notes, 2011
Background This study examined the associations of job control, organizational justice and bullying at the workplace with emotional exhaustion. This was done by adjusting firstly for age and occupational class, secondly physical work factors, thirdly ...
Saastamoinen Peppiina, Helkavaara Minna, Lahelma Eero   +2 more
doaj   +1 more source